模拟失重雌性大鼠L_5椎骨蠕变特性的研究

The Study on Creep Behavior of Simulated Weightlessness Female White Rat L5 Vertebrae

研究模拟失重对雌性大鼠承重骨流变特性的影响,为航天医学提供模拟失重动物椎骨流变学参数。30只雌性大鼠,随机分为正常对照组15只和头低位30°尾吊组(模型组)15只。实验第42 d时取两组动物L5椎骨进行压缩蠕变实验。得出了正常对照组和失重组(模型组)大鼠L5椎骨压缩蠕变数据和曲线,以三参数模型处理实验数据,得出了正常对照组和失重组大鼠L5椎骨应力松弛方程和蠕变方程。还得出了2组大鼠股骨蠕变与时间的变化规律。失重组大鼠L5椎骨7 200 s蠕变量低于正常对照组(P<0.05)。结果表明,失重骨质疏松对大鼠椎骨的流变特性具有一定影响。

To study the impact of simulated weightlessness on rheological properties of female rat′s bearing bone and provide parameters for space medicine.Thirty female rats were choosed and randomly divided into normal control group(fifteen)and sterns position 30° tail suspended group(model group-fifteen).On 28 th d after experiment,we took the animal s L5 vertebrae of two groups to carry on compression and creep test.We got the compression creep data and curve of white rats′ L5 vertebrae of two groups.The experimen...