多原发大肠癌16例临床分析

Analysis of diagnosis, treatment and prognosis in multi-originate colon carcinoma

目 的 探讨多原发大肠癌的诊断、治疗及预后。方法 对16例多原发大肠癌进行回顾性分析。结果 16例多原发大肠癌病人中同时癌10例,异时癌6例。术前均经纤维结肠镜检查及病理学确诊。全部病例均行手术治疗,手术切除率100％,并发症发生率12.5％。术后辅助化疗10例,放疗1例,复发率6.25％,转移率6.25％。5年生存率为70％。结论术前纤维结肠镜检查是发现同时性多原发大肠癌的重要手段。手术切除是多原发大肠癌最好的治疗方法。应根据病人及肿瘤具体情况,选择相应术式。及早诊治则预后较好。对随诊病人强调应用纤维结肠镜检查。

Objective To investigate the diagnosis, treatment and prognosis in multi-Originate colon carcinoma. Methods All 16 cases with multi-originate colon carcinoma from June 1975 to June 2001 in yuebei hospital were ana-lyzed retrospectively. Results 10 cases are synchronous carcinoma and 6 cases are metachronous carcinoma in all 16 cases. All cases underwent operation. Incidence of complication was 12.5% . 10 cases undenvent postoperative chemo-therapy and l case undenvent radiotherapy. Recurrence rate was 6.25% .Metastases rate was 6.25% . Five year survival rate was 70% . Conclusion Fiberoptic colonoscope is an ideal method to confirm diagnosis of multi-orginate colon carcinoma . Surgical resection is an effective treatment for multi-originate colon carcinoma. A correct method of surgical man-agement was selected according to the concrete situation of the patients. Fiberoptic colonoscopy should be emphasized for follow-up patients.