介入性超声治疗甲状腺良性结节的临床应用

Clinical application of interventional ultrasound therapy in the benign nodules of thyroid

目的评价介入性超声治疗甲状腺良性结节的临床应用价值。方法 246例甲状腺良性结节的患者在超声介入下进行无水乙醇或P胶体局部注射治疗,3个月和12个月后评32价治疗疗效。结果无水乙醇硬化治疗及P胶体治疗3个月和12个月总有效率分别为3291.8%,93.4%和91.9%,96.8%,两者无明显差异(P>0.05)。囊性病变疗效好于实性病变,12个月总有效率分别为100%和85.0%(P<0.01);32P胶体治疗实性病变稍优于无水乙醇治疗,12个月总有效率分别为90.9%和77.8%(P<0.05);对于囊性病变,两种治疗方法的效果无显著性差异(P<0.05)。结论介入性超声在治疗甲状腺良性结节中具有实用临床价值。

Objective To evaluate the opplied value of interventional ultrasound therapy in thyroid benign nodules.Methods 246 patients with thyroid benign nodules were treated with percutaneous ethanol injection(PEI)and radioactive colloidal chromium phosphated-32(RCCP)under the guidance of ultrasound,and the therapeautical results were evaluated 3 months and 12 months after treatment.Results Both ethanol and radioactive colloidal chromium phosphate-32 had significant effects in reducing the nodule size.The total effective rate was 91.8%,93.4%and91.9%,96.8% after 3 months and 12 months respectively and there was no obvious difference(P>0.05).But there was better effect in the cystic lesion than in the solid lesion,the total effective rate was 100% and 85.0% respectively in 12 months(P<0.01).But for the solid lesion,PEI was superior to RCCP,the effective rate was90.9% and 77.8%(P<0.05),but no difference between both methods in cyst lesions.Conclusion Interventional ultrasound therapy has clinical practical value in the treatment of thyroid benign nodules.