摘要
通过乙醛酸与壳聚糖形成西佛碱,用硼氢化钠还原制备N位取代的羧甲基壳聚糖,采用FT-IR、X-ray、NMR分析手段对分子结构进行表征。吸湿保湿性能研究发现取代度较低的N-羧甲基壳聚糖吸湿性能较好,保湿性能随着羧甲基取代度的增加而增强。通过羟基磷灰石、骨胶原与N-羧甲基壳聚糖制备了新型的复合生物材料,与没有添加N-羧甲基壳聚糖的复合材料相比较,发现具有良好的机械性能和溶涨性能。
N-carboxymethyl chitosan was prepared by adding glyoxylic acid and sodium hydroxide,with its molecular structure characterized by FT-IR,XRD and NMR.Its moisture-absorption and retention abilities were also studied.New composite biomaterial was made from hydroxyapatite and collagen conjugated with N-carboxymethyl chitosan.The structure evaluation of composite showed more dense arrangement due to formation of collagen-N-carboxymethyl chitosan conjugate,and particles of inorganic component were closely anchore...
出处
《环境科学与技术》
CAS
CSCD
北大核心
2010年第11期62-65,共4页
Environmental Science & Technology
基金
浙江省教育厅项目(Y200907046)
关键词
N-羧甲基壳聚糖
结构表征
吸湿保湿
复合材料
骨修复
N-carboxymethyl chitosan
structure characterization
moisture-absorption and retention
composite biomaterial
bone remediation
