脑梗死后血管性认知障碍的相关因素

Influence factors of vascular cognitive impairment in cerebral infarction

目的探讨脑梗死(CI)后血管性认知障碍(VCI)的影响因素。方法对76例经头部CT或MRI确诊的脑梗死患者和对照组进行比较,采用国际通用的简易智能状态检查量表(MMSE)、日常生活行为量表(ADL)和画钟测验(CDT)进行神经心理检查。结果 CI组患者认知功能障碍发生率明显高于对照组,CI组MMSE、ADL和CDT评分与对照组比较差异具有显著性。脑梗死患者中有卒中史组与无卒中史组比较,高血压组与血压正常组比较,同型半胱氨酸升高组与同型半胱氨酸正常组比较,差异具有显著性(均P<0.05)。结论脑梗死患者VCI发生率明显高于对照组,VCI发生与卒中史、高血压、糖尿病及血清同型半胱氨酸有关。

Objective To investigate the influential factors of vascular cognitive impairment after cerebral infarction(CI).Methods 76 CI patients were diagnosed by cranial CT or MRI and matched control group were analyzed with neuropsychological tests including mini-mental state examination(MMSE),activities of daily living scale(ADL)and clock drawing test(CDT).Results The incidence of cognitive impairment in CI group was higher than that in control group,the scores of MMSE、ADL、CDT in two groups were significantly different.Conclusion The incidence of vascular cognitive impairment in patients CI is higher than that in control group,vascular cognitive impairment is related to stroke、hypertension、diabetes mellitus and serum homocysteine.