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Separation of a tungus producing taxol 被引量:1

Separation of a tungus producing taxol
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摘要 An endogenous filariform fungus has been separated from a treenamed Taxus growing in the Aba region, Sichuan, China. The fungus is fermented in fluid medium for 3 weeks at 25℃, then the HPLC and MALDI-TOF analysis of the zymotic fluid show that the zymotic fluid contains taxol. So it is a fungus which can produce taxol. It is named Taxomyces sp. temporarily. An endogenous filariform fungus has been separated from a tree named Taxus growing in the Aba region, Sichuan, China. The fungus is fermented in fluid medium for 3 weeks at 25℃, then the HPLC and MALDI-TOF analysis of the zymotic fluid show that the zymotic fluid contains taxol. So it is a fungus which can produce taxol. It is named Taxomyces sp. temporarily.
出处 《Science China(Life Sciences)》 SCIE CAS 2001年第2期156-160,共5页 中国科学(生命科学英文版)
基金 the Sichuan Provincial Committee of Science and Technology, the Directors Fund of Chinese Academy of Sciences, and the DiAu Scientific Fund.
关键词 TAXOL filariform fungus Taxus. taxol, filariform fungus, Taxus.
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参考文献4

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同被引文献18

  • 1高山林,朱丹妮,周荣汉.东亚和北美产红豆杉属七种植物中紫杉醇及短叶醇的含量[J].中国药科大学学报,1995,26(1):8-10. 被引量:39
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  • 7WALKER K, CROTEAU R. Taxol biosynthetic genes [ J ].Phytochemistry, 2001, 58( 1 ) : 1-7.
  • 8EWALD D, STAUBER T, ZOCHER R. Evaluation and selection of Taxus baccata L. clones according to their root growth capacity as a potential source of enzymes for taxol biosynthesis [ J ]. Silvae Genetica, 2002, 51(4): 133-136.
  • 9KETCHUM R E B, RITHNER C D, QIU D Y, et al. Taxus metabolomics: methyl jasmonate preferentially induces production of taxoids oxygenated at C-13 in Taxus media cell cultures [J].Phytochemistry, 2003, 62(6): 901-909.
  • 10ZHONG J J. Plant cell culture for production of paclitaxel and other toxins[J]. Journal of Bioscience and Bioengineering, 2002, 94(6) :591-599.

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