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Molecular mechanism of effect of rotating constant magnetic field on organisms

Molecular mechanism of effect of rotating constant magnetic field on organisms
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摘要 The effect of RCMF-magnetic therapy apparatus on signal substances was studied. The radioimmunoassay (RIA) suggested that the magnetic field increased p-endorphin markedly in plasma. ELISA indicated that the magnetic field inhibited vomiting reaction induced by chemotherapy drug, with reversible decrease of serotonin (5-HT) level in brains, small intestine tissue and serum. Furthermore, the bioeffect of magnetic fields on 5-HT level presented a typical window effect and post-effect, and the inhibitory effect of magnetic field on the emesis was parallel to the decrease level of 5-HT. This result implied that the decrease of 5-HT might be the basis of rotating constant magnetic field (RCMF) inhibiting drug-induced emesis. The nitric acid reductase-spec-trophotometry and nicotinamide adenine dinucleotide-diaphorase/arginine-vasopressin (AVP) cytochemistry technique showed that the magnetic field induced nitric oxide (NO) increase in hypo-thalamus and the high NO(A) level lasted for 3 hours. The results suggested that NO(A) increases after the treatment of the magnetic field in hypothalamus, which may result from strong expression of NO-ergic neuron in paraventricular hypothalamic nucleus (PVN), periventricular hypothalamic nucleus (PEN) and supraoptic nucleus (SON). The coexistence of NO and AVP may play an important role in the regulation of endocrine and neuroendocrine by the magnetic field. And our data also confirmed that the magnetic field increased the content of NO so strongly that high NO level lasted for 3 hours, also made neuropeptide Y (NPY) cell in medulla stained heavily. The effect of RCMF-magnetic therapy apparatus on signal substances was studied. The radioimmunoassay (RIA) suggested that the magnetic field increased β-endorphin markedly in plasma. ELISA indicated that the magnetic field inhibited vomiting reaction induced by chemotherapy drug, with reversible decrease of serotonin (5-HT) level in brains, small intestine tissue and serum. Furthermore, the bioeffect of magnetic fields on 5-HT level presented a typical window effect and post-effect, and the inhibitory effect of magnetic field on the emesis was parallel to the decrease level of 5-HT. This result implied that the decrease of 5-HT might be the basis of rotating constant magnetic field (RCMF) inhibiting drug-induced emesis. The nitric acid reductase-spectrophotometry and nicotinamide adenine dinucleotide-diaphorase/arginine-vasopressin (AVP) cytochemistry technique showed that the magnetic field induced nitric oxide (NO) increase in hypothalamus and the high NO(A) level lasted for 3 hours. The results suggested that NO(A) increases after the treatment of the magnetic field in hypothalamus, which may result from strong expression of NO-ergic neuron in paraventricular hypothalamic nucleus (PVN), periventricular hypothalamic nucleus (PEN) and supraoptic nucleus (SON). The coexistence of NO and AVP may play an important role in the regulation of endocrine and neuroendocrine by the magnetic field. And our data also confirmed that the magnetic field increased the content of NO so strongly that high NO level lasted for 3 hours, also made neuropeptide Y (NPY) cell in medulla stained heavily.
出处 《Science China(Life Sciences)》 SCIE CAS 2001年第5期554-560,共7页 中国科学(生命科学英文版)
关键词 rotating constant magnetic field (RCMF) Β-ENDORPHIN serotonin (5-HT) nitric oxide (NO) neuropeptide Y(NPY). rotating constant magnetic field (RCMF), β-endorphin, serotonin (5-HT), nitric oxide (NO), neuropeptide Y(NPY).
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参考文献11

  • 1A. Bois M.D.,H. G. Meerpohl M.D.,H. Kriesinger-Schroeder.The role of serotonin as a mediator of emesis induced by different stimuli[J].Supportive Care in Cancer.1995(5)
  • 2Zhang, X. Y,Liu, D,Zhang, X. E. et al.Study of effect of magnetic field on cell growth and division[].Science in China.1989
  • 3Zhang, X. Y,Zhang, X. E,Liu, D.The effect of strong constant magnetic field on cell growth and division[].Chinese Science.1989
  • 4Zhang, X. Y,Zhang, W. D,Lu, L.Study of effect of magnetic field on cells[].Basic Medicine and Clinic.1994
  • 5Zhang, X. Y,Luo, Z. G,Ma, Y. J.Influence of magnetic field on P-endorphin in plasma[].Chinese J Physical Medicine.1998
  • 6Zhang, X. Y,Luo, Z. G,Ma, Y. I.Influence of magnetic field on P-endorphin in plasma[].Chinese J Physical Medicine.1998
  • 7Husain, A,DeSilva, P,Speth, R. C. et al.Regulation of angiotensin II in rat adrenal gland[].Circulation Research.1987
  • 8Millatt, L. J,Abdel-Rahman E. M,Siragy, H. M.Angiotensin II and nitric oxide: a question of balance[].Regul Rept.1993
  • 9Du Bois A,Kriesinger-Schroeder H,Meerpohl H G.The role of serotonin as a mediator of emesis induced by different stimuli[].Supportive Care in Cancer.1995
  • 10Miller J D.On the circadian clock in mammals[].American Journal of Physiology.1993

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