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The prognostic value of preoperative serum levels of CEA,CA19-9 and CA72-4 in patients with colorectal cancer 被引量：25

The prognostic value of preoperative serum levels of CEA,CA19-9 and CA72-4 in patients with colorectal cancer
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摘要 INTRODUCTIONCarcinoembryonic antigen ( CEA) , originally described by Gold and Freedman [1] in 1965, is now an acknowledged member of immunoglobulin superfamily[2],with a role as an intracellular adhesion molecule[3].Carbohydrate antigen 19-9(CA19-9), obtained with a monoclonal antibody produced by immunizing a monoclonal antibody produced by immunizing a mouse with a colonic cancer cell line in 1979[4],is a ligand for E-selectin that plays an important role in the addhesion of cancer cells to endothelial cells [5,6].
作者 Chao Xu Zheng~1 Wen Hua Zhan~1 Ji Zong Zhao~2 Dong Zheng~3 Dong Ping Wang~1 Yu Long He~1 Zhang Qing Zheng~1 ~1Department of General Surgery,~2Laboratory of Surgery,~3Department of Medicine,First Affiliated Hospital,Sun Yat-Sen University of Medical Sciences,Guangzhou 510080,Guangdong Province,ChinaDr.Chao Xu Zheng now working as a surgeon and lecturer in the Department of General Surgery,First Affiliated Hospital,Sun Yat-Sen University of Medical Sciences,who is a Ph.D.student,having 7 papers published.
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2001年第3期431-434,共4页 世界胃肠病学杂志（英文版）
基金 This study was supported by the research grant from Administration of Key Disciplines for"Project 211"of Sun Yat-Sen University of Medical Sciences,Grant No.98097.
关键词 tumor markers/biological COLORECTAL neoplasms/surgery COLORECTAL neoplasms/blood carcinoembryonic antigen/serum CA19-9 antigen/ SERUM antigens tumor-associated.carbohydrate/serum prognosis tumor markers/biological colorectal neoplasms/surgery colorectal neoplasms/blood carcinoembryonic antigen/serum CA19-9 antigen/serum antigens,tumor-associated,carbohydrate/serum prognosis
分类号 R735.3 [医药卫生—肿瘤]
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参考文献14

  • 1Takashi Ueda,Etsuji Shimada,Tomoaki Urakawa.The clinicopathologic features of serum CA 19-9-positive colorectal cancers[J].Surgery Today.1994(6)
  • 2G. V. Kornek,D. Depisch,H. R. Rosen,E. M. Temsch,W. Scheithauer.Comparative analysis of CA72-4, CA195 and carcinoembryonic antigen in patients with gastrointestinal malignancies[J].Journal of Cancer Research and Clinical Oncology.1992(4)
  • 3Claudio Fucini M.D.,Silvia Maria Tommasi M.D.,Dr. Stefano Rosi M.D.,Giorgio Malatantis M.D.,Gaetano Cardona M.D.,Sergio Panichi M.D.,Ugo Bettini M.D.Follow-up of colorectal cancer resected for cure[J].Diseases of the Colon & Rectum.1987(4)
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  • 7Nakayama T,Watanabe M,Teramoto T,Kitajima M.CA19-9 as a predictor of recurrence in patients with colorectal cancer[].Journal of Surgical Oncology.1997
  • 8Ohuchi N,Takahashi K,Matoba N,Sato T,Taira Y,Sakai N,Masuda M,Mori S.Comparison of serum assays for TAG-72,CA19-9,and CEA in gastrointestinal carcinoma patients[].Japanese Journal of Clinical Oncology.1989
  • 9Giovannini M,Bernardini D,Seitz JF,Moutardier V.Hoevenaeghel G,Monges G,Delpero JR.Value of endoscopic ultrasonography for assessment of patients presenting elevated tumor marker levels after surgery for colorectal cancers[].Endoscopy.1998
  • 10Berg EL,Magnani J,Wamock RA,Robinson MK,Butcher EC.Comparison of L-selectin and E-selectin ligand apecificities:the L-selectin can bind the E-selectin ligands sialyl Le~x and sialyl Le~a[].Biochemical and Biophysical Research Communications.1992

共引文献5

同被引文献236

  • 1钟礼瀑,靳文剑,邹学森,吴青青,刘敏知,吴建国,蔡芸.血清LTA和CEA检测对非小细胞肺癌的诊断价值[J].实验与检验医学,2007,25(6):546-548. 被引量：2
  • 2Yong Chuan Deng1,Yong Su Zhen2,Shu Zheng1,Yu Chuan Xue2 1Cancer Institute, Medical School, Zhejiang University, Hangzhou 310009, Zhejiang Province, China2Institute of Medicinal Biotechnology, CAMS & PUMC, Beijing 100050, China.Activity of boanmycin against colorectal cancer[J].World Journal of Gastroenterology,2001,7(1):93-97. 被引量：5
  • 3Ping Yuan~1 Meng Hong Sun~2 Jin Sheng Zhang~1 Xiong Zeng Zhu~2 Da Ren Shi~2 ~1Department of Pathology,Medical College of Fudan University,~2Department of Pathology,Cancer Hospital/Cancer Institute,Fudan University,Shanghai 200032,ChinaDr.Ping Yuan Studying Province.studying in Medical College of Fudan University,worked in Department of Pathology,Wannan Medical College,having eighteen papers published..APC and K-ras gene mutation in aberrant crypt foci of human colon[J].World Journal of Gastroenterology,2001,7(3):352-356. 被引量：20
  • 4Jun Hui Cui~1 Uwe Krueger~2 Doris Henne-Bruns~2 Bemd Kremer~2 Holger Kalthoff~2 ~1Department of General Surgery,First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou 310003,Zhejiang Province,China ~2Department of General Surgery,Christian-Albrechts-University,Kiel,GermanyDr.Jun Hui Cui graduated from Zhejiang Medical University in 1984,earned master degree in 1990,studied in the Surgical Department of Kiel University and worked in the Lab of Molecular Oncology of Kiel University from 1994-1997achieved M.D.from Kiel University.Germany,now associate professor of surgery,specialized in colorectal oncology.Adviser of graduated student for master degree,having 20 publications published in key Chinese or English journals..Orthotopic transplantation model of human gastrointestinal cancer and detection of micrometastases[J].World Journal of Gastroenterology,2001,7(3):381-386. 被引量：19
  • 5Xiao Wei Li~1 Yan Qing Ding~1 Jun Jie Cai~1 Shao Qing Yang~2 Lian Bing An~3 Dong Fang Qiao~3 ~1Department of Pathology,Nanfang Hospital of the First Military Medical University,Guangzhou 510515,Guangdong Province,China ~2The Northern Hospital of PLA,Shenyang 110015,Liaoning Province,China ~3Department of Electronmicroscopy,First Military Medical University,Guangzhou 510515,Gangdong Province,ChinaDr.Xiao Wei Li graduated from the First Military Medical University with a MM degree in 1999.Physician in Charge of pathology,having 6 papers published..Studies on mechanism of Sialy Lewis-X antigen in liver metastases of human colorectal carcinoma[J].World Journal of Gastroenterology,2001,7(3):425-430. 被引量：19
  • 6Li Ping Wang~1 Ke Liang~2 Yu Shen~2 Wei Bo Yin~2 G.Hans~3 Yan Jun Zeng~1 ~1Biomechanics & Medical Information Institute,Beijing Polytechnic University,Beijng 100022,China ~2Department of Gastrointestinal Surgery,Aalborg University,Denmark ~3Cancer Institute (Hospital),Chinese Academy of Medical Sciences,Peking Union Medical College,Beijing 100021,ChinaLi Ping Wang graduated from Beijing Polytechnic University in 2000,major in tumor radiotherapy,having 3 papers published..Neutron-induced apoptosis of HR8348 cells in vitro[J].World Journal of Gastroenterology,2001,7(3):435-439. 被引量：5
  • 7Xiao-Hui Si Lian-Jun Yang Research Institute of Stomatology,the Ninth People’s Hospital,Shanghai Second Medical University,Shanghai 200011,ChinaDepartment of Pathology,Fourth Military Medical University,Xi’an 710033,Shaanxi Province,China.Extraction and purification of TGFβ and its effect on the induction of apoptosis of hepatocytes[J].World Journal of Gastroenterology,2001,7(4):527-531. 被引量：15
  • 8Xing-Guo Li Jin-Dan Song Yun-Qing Wang Key Laboratory of Cell Biology,Ministry of Public Health of China,China Medical University,Shenyang 110001,Liaoning Province,China.Differential expression of a novel colorectal cancer differentiation-related gene in colorectal cancer[J].World Journal of Gastroenterology,2001,7(4):551-554. 被引量：7
  • 9GregoryBMakin,DavidJBreen,JohnRTMonson.The impact of new technology on surgery for colorectal cancer[J].World Journal of Gastroenterology,2001,7(5):612-621. 被引量：21
  • 10Jing Yi~1 Zhi-Wei Wang~1 Hui Cang~1 Yu-Ying Chen~1 Ren Zhao~2 Bao-Ming Yu~2 Xue-Ming Tang~1 1 Department of Cell Biology,2 Department of Surgery,Ruijin Hospital,Shanghai Second Medical University,Shanghai 200025,China.p16 gene methylation in colorectal cancers associated with Duke's staging[J].World Journal of Gastroenterology,2001,7(5):722-725. 被引量：21

引证文献25

二级引证文献242

World Journal of Gastroenterology
2001年 第3期

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