PTC法合成E-4,5-二取代苯基-2-吡咯烷酮

Synthesis of Trans-4,5-Disubstituted-2-Pyrrorlidinones by Phase Transfer Catalysis

采用PTC法合成了E - 4,5 -二取代苯基 - 2 -吡咯烷酮 ,反式异构体与顺式异构体之比为 97∶3,产率高达 74% ,其结构用1HNMR和MS表征。

E-4,5-Disubstituted-2-Pyrrolichinones was synthesized under phase transfer catalysis,trans:cis was 97:3,The yield of the product was 74%,Structures of product was confirmed by 1 HNMR and MS.