摘要
内皮细胞损伤是糖尿病血管病变的基础,而高血糖引发的氧化应激,进而激活NF-KB、PKC等信号通路,对血管内皮细胞损伤起重要作用。针对抗氧化的病因学治疗是糖尿病并发症预防和治疗的关键。笔者对此作一综述。
Endodermis cell injury is the base of diabetic vascular lesion,and high glucose can cause oxidation stress and stimulate signal path of NF-KB,PKC,which can injure vascular endodermis cell.The treatment pointing to the etiology is the key to diabetic complication.Thereof the author expounds it.
出处
《浙江中医药大学学报》
CAS
2010年第6期944-946,共3页
Journal of Zhejiang Chinese Medical University
关键词
糖尿病
氧化应激
内皮细胞
血管病变
diabetes
oxidation stress
endodermis cell
vascular lesion
