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血运重建对急性前壁心肌梗死后1年内心功能的影响

Effects of revascularization on left ventricular remodeling and function in patients with acute anterior myocardial infarction.
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摘要 目的评价血运重建与否及不同时机血运重建对前壁急性心肌梗死(AMI)后心室重构和心功能的影响。方法将44例前壁AMI患者按不同的治疗方法分为药物治疗组(药物组,n=17)、急诊血运重建组(急诊组,n=11)、择期血运重建组(择期组,n=16)。分别检测AMI后1周、3个月、6个月及1年的左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)、左室射血分数(LVEF),二尖瓣舒张早期血流速度(VE)和二尖瓣心房收缩期血流速度(VA),并计算VE和VA的比值(VE/VA)。结果急诊组6个月的LVESD、6个月和12个月的LVEDD及择期组3个月和6个月的LVESD、3个月、6个月和12个月的LVEDD低于同期药物组(P<0.05);急诊组6个月的LVEF和VE/VA、择期组6个月的LVEF高于药物组同时点(P<0.05);急诊组和择期组组间各时点同期的LVEDD、LVESD、LVEF和VE/VA的差异均无显著性(P>0.05)。三组组内各个时点间的LVEDD、LVESD、LVEF和VE/VA的差异均无显著性(P>0.05)。结论血运重建抑制前壁AMI后的心室重构、改善左室收缩功能的效果优于单纯药物治疗,急诊血运重建在改善心脏舒张功能方面具有更大的优势。 Objective To evaluate the effects of revascularization on left ventricular remodeling,left ventricular systolic and diastolic function in patients with acute anterior myocardial infarction(AAMI).Methods According to the different therapies,forty-four patients with AAMI were divided into 3 groups which were conventional therapy group(n=17),emergency revascularization group(n=11) and selective revascularization group(n=16).The left ventricular end-diastolic dimension(LVEDD),left ventricular end-systolic dimen...
出处 《贵州医药》 CAS 2011年第3期207-210,共4页 Guizhou Medical Journal
基金 贵州省科学技术基金资助项目[黔基合计字(2003)3043] 贵州省高层次人才科研条件特助经费资助项目[黔人领函(2005)14]
关键词 心肌梗死 前壁 血运重建 心室重构 心功能 超声心动图 Myocardial infarction anterior Revascularization Ventricular remodeling Left Ventricular function Echocardiography
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