276例Ⅰ类切口手术围术期预防性应用抗菌药物调查分析

Investigation of 276 Cases of Perioperative Prophylactic Application of Antibiotics in Type Ⅰ Incision Operations

目的:评价某"三甲"医院Ⅰ类切口手术围术期预防性应用抗菌药物情况。方法:采用回顾性方法,对某"三甲"医院2009年7月276例脑外科和骨外科Ⅰ类切口手术患者的住院时间、用药时间、用药种类、费用等指标进行统计、分析。结果:276例患者中,抗菌药物预防性应用率达99.64%(275例),共776例/次,平均用药2.81次;术前首次预防用药>2h者222例(80.43%),平均用药时间为9.61d,最长达34d;预防性应用抗菌药物共涉及10类38种,应用频次排序列前3位的依次为头孢替安(117例/次)、氟氯西林(77例/次)、哌拉西林/舒巴坦(74例/次);单一用药173例(62.68%),联合用药102例(36.96%)。结论:该院Ⅰ类切口手术围术期预防性应用抗菌药物仍存在较严重不规范现象,亟待采取相关措施加以干预。

OBJECTIVE: To evaluate the perioperative prophylactic application of antibiotics in typeⅠincision operation. METHODS: By retrospective analysis, the hospitalization time, medication duration, category of drugs and drug expenditure of patients underwent type Ⅰ incision operation in neurologic surgery and orthopedic department in Jul. 2009 were analyzed statistically. RESULTS: Of total 276 cases, prophylactic application of antibiotics accounted for 99.64% (275 cases) with total times of drug use of 776. The ...