动脉狭窄TCD微栓子监测与血管性认知功能障碍的相关性研究

Study of the correlation of microembolus monitoring by TCD and vascular cognitive impairment in artery stenosis patients

目的通过经颅彩色多谱勒(TCD)对患者血管狭窄的检测及微栓子监测和蒙特利尔认知评(MOCA)量表评分,探讨微栓子监测与血管狭窄及血管性认知障碍的相关性。方法总结我院经TCD检查诊断为颈内动脉起始段(ICAex)或大脑中动脉(MCA)M1段狭窄患者82例。根据收缩期血流速度、频谱形态、音频情况将患者血管狭窄程度大致分为极度狭窄(A组)、重度狭窄(B组)、中度狭窄(C组)和正常对照组(D组)30例。应用经颅多普勒(TCD)对脑循环中微栓子(MES)进行检测,蒙特利尔认知评估(MOCA)量表评分。结果 B组MES的发生率较C组高;A组MES的发生频率较B组高。A组可见微栓子信号的8例患者蒙特利尔认知评分均低于B组可见微栓子信号的11例患者,B组可见微栓子信号的患者蒙特利尔认知评分,低于C组可见微栓子信号的3例患者。结论血管性认知障碍与血管狭窄及微栓子数量有明显相关性。

Objective This study was about to find the correlation of microembolus monitoring,arterystenosis by transcranial Doppler(TCD) and cognitive impairment by Montreal cognitive assessmert(MOCA) rating scale.Methods Retrospective summary of 82 patients who were diagnosed by TCD with the stenosis of internal carotid artery(starting ICAex) or middle cerebral artery(MCA).All patients were roughly divided into three groups,extreme stenosis group(group A),severe stricture group(group B) and medium group(group C) acco...