90例中药严重(新的严重)不良反应分析

Analysis of 90 cases serious(serious and new) adverse reactions of Chinese medicine

目的:了解中药不良反应在临床中的发生情况,发挥药品不良反应监测工作在安全用药中的指导作用。方法:采用回顾性分析研究方法,对临床发生的90例中药严重、新的严重不良反应进行综合分析。结果:中药严重不良反应91.55%以上发生在静脉给药,中药注射液ADR多数发生在静脉给药10分钟内;新的严重不良反应63.16%发生在口服制剂。结论:中药不良反应与给药途径有相关性。口服中药制剂安全信息尚需不断完善。

Objective:To understand adverse drug reactions(ADRs) of Chinese medicine and guide the safe use of Chinese medicine by ADR monitoring.Method:90 cases of serious and new serious ADRs of Chinese medicine in clinical were analyzed by retrospective methods.Result:91.55% of ADRs happened in Chinese medicine injections and most cases happened in the first 10 minutes.63.16% of new serious ADRs happened in Chinese medicine oral preparations.Conclusion:ADRs of Chinese medicine are related to the administration route.And the safe information of Chinese medicine oral preparations needs to be consummated.