期刊文献+

子前期-子并发症发生机制的研究 被引量:3

Pathogenesis of complications of pre-eclampsia and eclampsia
下载PDF
导出
摘要 子前期是妊娠期特有疾病之一,以妊娠期高血压和蛋白尿为主要临床表现,如不进行有效治疗,可进一步发展为子,并可产生心血管、肾脏、脑、血液、消化等各系统的严重并发症,严重威胁孕产妇及新生儿的生命。子前期发病机制尚未完全明确,目前认为胎盘低灌注是其病理基础,引起母体血管内皮细胞损伤,从而导致全身各系统功能障碍。文章主要对子前期-子并发症的发生机制、发病率以及研究进展进行综述。 Pre eclampsia is a disorder that is unique to pregnancy, with gestational hypertens ion and proteinuria asmain clinica lmanifestations. W ithout proper management, pre eclamps ia may develop to eclampsia and cause a series of complications involving card iovascular, rena,l neurologic, hematologic and gastrointestinal systems, wh ich may threaten lives of mothers and infants. The pathogenes is of pre eclamps ia is still unclear, and reduced placenta l perfus ion is cons idered to be the pathologicalmechan ism, wh ich may result in endothelial cell in jury and further aggravate dysfunction of maternal systems. Th is paper reviews the pathogenes is, incidence and research progress of complications of pre eclamps ia and eclampsia.
出处 《上海交通大学学报(医学版)》 CAS CSCD 北大核心 2011年第5期676-680,共5页 Journal of Shanghai Jiao tong University:Medical Science
关键词 子前期 并发症 pre-eclampsia eclampsia complication
  • 相关文献

参考文献41

  • 1上海市妊娠高血压综合征调查协作组,黄亚绢,苏琪枫,顾玮,潘明明,顾蔚云,荆铭,王德芬,裘佳敏,赵欣,范晓芳,陆琴,金婉玲,江明礼,申玉红,董玉英,沙金燕,古航,黄亚绢,梅丽萍,戴钟英.上海市10年妊娠高血压综合征发病的研究[J].中华妇产科杂志,2001,36(3):137-139. 被引量:75
  • 2Gülseren Yücesoy,Sebiha ?zkan,Harika Bodur,Temel Tan,Eray ?al??kan,Birol Vural,Ayd?n ?orak??.Maternal and perinatal outcome in pregnancies complicated with hypertensive disorder of pregnancy: a seven year experience of a tertiary care center[J]. Archives of Gynecology and Obstetrics . 2005 (1)
  • 3Terrone DA,Isler CM,May WL,et al.Cardiopulmonary morbidityas a complication of severe preeclampsia HELLP syndrome. JPerinatol . 2000
  • 4Gilbert JS,Ryan MJ,LaMarca BB,et al.Pathophysiology of hyper-tension during preeclampsia:linking placental ischemia with endo-thelial dysfunction. American Journal of Physiology Heart and Circulatory Physiology . 2008
  • 5Zhou CC,Zhang Y,Irani RA,et al.Angiotensin receptor agonisticautoantibodies induce pre-eclampsia in pregnant mice. NatMed . 2008
  • 6Tuffnell DJ,Jankowicz D,Lindow SW.et al.Outcomes of severepre-eclampsia/eclampsia in Yorkshire 1999/2003. BJOG . 2005
  • 7Stepan H,Jank A.Angiogenic factors and their role in pathogenesisand prediction of preeclampsia. Zeitschrift fur Geburtshilfe und Neonatologie . 2009
  • 8Khan KS,Wojdyla D,Say L,et al.WHO analysis of causes ofmaternal death:a systematic review. The Lancet . 2006
  • 9Page EW.The relation between hydatid moles,relative ischemia ofthe gravid uterus,and the placental origin of eclampsia. American Journal of Obstetrics and Gynecology . 1939
  • 10Khalil RA,Granger JP.Vascular mechanisms of increased arterialpressure in preeclampsia:lessons from animal models. American Journal of Physiology . 2002

二级参考文献4

  • 1郑怀美.妇产科学(第3版)[M].北京:人民卫生出版社,1994.95-139,205-216.
  • 2郑怀美,妇产科学(第3版),1994年,114页
  • 3全国妊高征科研协作组,中华妇产科杂志,1991年,26卷,67页
  • 4钱尚萍,蒋迪仙.全国妊高征的流行病学调查[J].中华妇产科杂志,1991,26(2):67-70. 被引量:79

共引文献74

同被引文献28

  • 1高培国,强辉,凌鸣.葛根素对过氧化氢诱导的血管内皮细胞损伤的保护作用[J].西安交通大学学报(医学版),2012,33(2):245-248. 被引量:45
  • 2袁佩,虞斌,王秋伟,傅银峰,董一善.重度妊高征肝肾功能变化及其围产儿结局的探讨[J].中国临床医学,2005,12(4):680-681. 被引量:8
  • 3Lind T,Godfrey KA,Otun H,et al.Changes in serum uric acidconcentrations during normal pregnancy[J] .Br J Obstet Gyn-aecol,1984,91(2):128-132.
  • 4Koopmans CM,van Pampus MG,Groen H,et al.Accuracyofserum uric acid as a predictive test for maternal complica-tions in preeclampsia:bivariate meta-analysis and decisionanalysis[J] .Eur J Obstet Gynecol Reprod Biol,2009,146(1):8-14.
  • 5D’Anna R,Bavicra G,Scilipoti A,et al.The clinical utilityof serum uric acid measurements in pre-eclampsia and tran-sient hypertension in pregnancy[J] .Panminerva Med,2000,42(2):101-103.
  • 6Bainbridge SA,Roberts JM.Uric acid as a pathogenic factor inpreeclampsia[J] .Placenta,2008,29(Suppl A):S67-S72.
  • 7Kanbay M,Solak Y,Dogan E,et al.Uric acid in hypertensionand renal disease:the chicken or the egg?[J] .Blood Purif,2010,30(4):288-295.
  • 8MartinAC,Brown MA.Could uric acid have a pathogenic rolein preelampsia?[J] .Nat Rev Nephrol,2010,6(12):744-748.
  • 9Laughon SK,Catov J,Powers RW,et al.First trimester uricacid and adverse pregnancy outcomes[J] .Am J Hypertens,2011,24(4):489-495.
  • 10A. Maebayashi,T. Yamamoto,H. Azuma,E. Kato,S. Kuno,T. Murase,F. Chishima.PP121. Expression of PlGF, sFlt, MTF-1, HO-1 and HIF-1 alpha mRNAs in preeclampsia placenta and effect of preeclampsia sera on their expression of choriocarcinoma cells[J].Pregnancy Hypertension: An International Journal of Women’s Cardiovascular Health.2012(3)

引证文献3

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部