摘要
子前期是妊娠期特有疾病之一,以妊娠期高血压和蛋白尿为主要临床表现,如不进行有效治疗,可进一步发展为子,并可产生心血管、肾脏、脑、血液、消化等各系统的严重并发症,严重威胁孕产妇及新生儿的生命。子前期发病机制尚未完全明确,目前认为胎盘低灌注是其病理基础,引起母体血管内皮细胞损伤,从而导致全身各系统功能障碍。文章主要对子前期-子并发症的发生机制、发病率以及研究进展进行综述。
Pre eclampsia is a disorder that is unique to pregnancy, with gestational hypertens ion and proteinuria asmain clinica lmanifestations. W ithout proper management, pre eclamps ia may develop to eclampsia and cause a series of complications involving card iovascular, rena,l neurologic, hematologic and gastrointestinal systems, wh ich may threaten lives of mothers and infants. The pathogenes is of pre eclamps ia is still unclear, and reduced placenta l perfus ion is cons idered to be the pathologicalmechan ism, wh ich may result in endothelial cell in jury and further aggravate dysfunction of maternal systems. Th is paper reviews the pathogenes is, incidence and research progress of complications of pre eclamps ia and eclampsia.
出处
《上海交通大学学报(医学版)》
CAS
CSCD
北大核心
2011年第5期676-680,共5页
Journal of Shanghai Jiao tong University:Medical Science
关键词
子前期
子
并发症
pre-eclampsia
eclampsia
complication