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细胞色素P450 4F2基因多态性的研究进展

Research progress of single nucleotide polymorphisms of cytochrome P450 4F2
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摘要 细胞色素P450(CYP)4F2是CYP的亚型,参与体内一系列生化反应。新近的研究发现了它在心脑血管及血液学领域等方面新的生理机制,由此可以从多个角度全新解释相关领域的疾病及病理生理过程,如原发性高血压、心肌梗死、脑卒中及脂类物质花生四烯酸和药物华法林等在体内的代谢等。 Cytochrome P450(CYP) 4F2,a member of the CYP4F enzyme subfamily,takes part in a series of biochemical reaction in vivo.Recent researches have revealed the new mechanism the enzyme plays in the cardiovascular and hematological fields,such as essential hypertension,myocardial infarction,stroke and metabolism of arachidonic acid and warfarin.
作者 李劼慧 徐建军
机构地区 南昌大学第二附属医院心胸外科
出处 《上海交通大学学报（医学版）》 CAS CSCD 北大核心 2011年第6期858-861,共4页 Journal of Shanghai Jiao tong University:Medical Science
关键词 细胞色素P450 基因多态性 病理生理 cytochrome P450 single nucleotide polymorphisms pathophysiology
分类号 Q559.9 [生物学—生物化学]
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参考文献25

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二级参考文献13

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共引文献1

上海交通大学学报（医学版）
2011年 第6期

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