自体心包补片在婴幼儿简单室间隔缺损修补中的应用

Application of autologous pericardial patch in repairing simple ventricular septal defect of infants

目的探讨戊二醛固定的自体心包补片在修补婴幼儿室间隔缺损(VSD)中的效果。方法 403例婴幼儿VSD患者均采用戊二醛固定的自体心包补片进行修补。结果无一例患儿出现术后溶血、感染、三度房室传导阻滞以及形成动脉瘤样膨出。29例患者出现残余分流,随访时间1.5个月～2年,其中26例患者残余分流消失,3例患者残余分流未愈合但无需再次手术。残余分流率在各年龄段、各类型VSD之间差异无统计学意义(P>0.05)。结论戊二醛固定的自体心包是修补婴幼儿简单VSD的良好材料。

Objective To investigate the outcomes of autologous pericardial patch treated by glutaraldehyde in repairing simple ventricular septal defect of infants.Methods Four hundred and three infants with ventricular septal defect were selected,and the ventricular septal defect was repaired with autologous pericardial patch treated by glutaraldehyde.Results No patient experienced hemolysis,infection,three-degree atrioventricular block and aneurysmal dilation after operation.Residual shunt occurred in 29 patients.Patients were followed up for 1.5 months to 2 years,the residual shunt disappeared in 26 patients,and that of the other 3 patients was not healed,while none needed a second operation.There was no significant difference in the rates of residual shunt among patients with different ages and different types of ventricular septal defect(P>0.05).Conclusion Autologous pericardial patch treated by glutaraldehyde is a good material for repairing simple ventricular septal defect of infants.