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我国的疫苗生产及监管对策研究 被引量:2

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摘要 我国将注射剂、生物制品和特殊药品列为高风险产品进行重点监管,而疫苗又是高风险产品监管的重中之重,本文旨在通过对三个疫苗品种生产工艺的关注,将风险关口前移至生产阶段,探究产品形成之前可能发现危险因素的各个环节,拓宽疫苗质量控制的思路,规避疫苗的使用风险。
出处 《上海食品药品监管情报研究》 2011年第3期6-10,共5页
关键词 疫苗 生产 监管
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同被引文献24

  • 1Park H,Adamson L,Ha T. Polyinosinic-polycytidylic acid is the most effective TLR adjuvant for SIV Gag proteininduced T cell responses in nonhuman primates[J].{H}Journal of Immunology,2013,(8):4103-4115.
  • 2Huang YK,Zheng Z,Cheng CX. The antitumor effect of the toll-like receptor 3 ligand polyinosinic-cytidylic acid as an adjuvant[J].{H}Cancer Immunology lmmunotherapy,2013,(2):237-244.
  • 3Cao Y,Lu Z,Li Y. Poly (I:C) combined with multi-epitope protein vaccine completely protects against virulent foot-and-mouth disease virus challenge in pigs[J].{H}Antiviral Research,2013,(2):145-153.
  • 4Li YG,Siripanyaphinyo U,Tumkosit U. Poly (I:C),an agonist of toll-like receptor-3,inhibits replication of the Chikungunya virus in BEAS-2B cells[J].{H}VIROLOGY JOURNAL,2012,(1):114-121.
  • 5Cao Y,Lu Z,Li P. Improved neutralising antibody response against foot-and-mouth-disease virus in mice inoculated with a multi-epitope peptide vaccine using polyinosinic and poly-cytidylic acid as an adjuvant[J].{H}Journal of Virological Methods,2012,(1):124-128.
  • 6Inao T,Harashima N,Monma H. Antitumor effects of cytoplasmic delivery of an innate adjuvant receptor ligand,poly (I:C),on human breast cancer[J].{H}Breast Cancer Research and Treatment,2012,(1):89-100.
  • 7Charerntantanakul W. Adjuvants for porcine reproductive and respiratory syndrome virus vaccines[J].{H}Veterinary Immunology and Immunopathology,2009,(1-2):1-13.
  • 8王厚廷,杨俊卿.派驻驻厂监督员经验谈[J].首都医药,2008(2):9-11. 被引量:2
  • 9朱月辉,陈叶平.驻厂监督员要当好“五员”[J].中国药事,2008,22(5):387-388. 被引量:2
  • 10吴世福.药品生产驻厂监督工作探讨[J].齐鲁药事,2008,27(7):392-393. 被引量:1

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