全身弥散加权成像对非小细胞肺癌诊断的价值

The study of whole body diffusion weighted imaging for diagnosis in non-small cell lung cancer

目的:探讨全身弥散加权成像(WB-DWI)对非小细胞肺癌的诊断价值。方法:对病理确诊的31例非小细胞肺癌的患者行全身弥散加权成像检查,将结果按病灶解剖部位不同分为4组,即肺内、纵膈内、远处淋巴结区、远处器官区,分别与病理及CT和(或)MRI的检查结果进行统计、分析。结果:与病理结果对照,四组不同解剖部位病灶检出率分别为90.3%、66.7%、81.8%、100%。与CT和(或)MRI结果对照,四组不同解剖病灶敏感性分别为65.12%,39.76%、98%、97.15%,特异性为100%、96.97%、63.04%、26.47%,差异有统计学意义(P(0.05)。结论:全身弥散加权成像对非小细胞肺癌远处淋巴结及器官转移的诊断优于CT和/或MRI,可以作为非小细胞肺癌诊断一种手段。

Objective:To investigate the value of WB-DWI for diagnosis of non-small cell lung cancer.Methods:WB-DWI images of 31 patients who had undergone surgery or chemoradiotherapy for histopathological proven non-small cell lung cancer were analyzed.The results were divided four groups by different anatomic site such as: in lung,in mediastinum,in distant place lymph nodal region and organ region.Besides,images were retrospectively assessed by visual inspection and the imaging findings were compared with histopathological findings and compared with the results of CT/MRI.Results:Compared with histopathologically results the accuracy of WB-DWI results for detecting staging were 90.3%,66.7%,81.8%,100%.Compared with CT/MRI,the sensitivity is 65.12%,39.76%,98%,97.15%,the specificity is 100%,96.97%,63.04%,26.47%.Conclusion:WB-DWI is superior for the detection of lymph node and organ metastases,and it can be used in diagnosis of NSCLC.