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羧甲基壳聚糖季铵盐作为基因载体及动物体内分布研究 被引量:2

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摘要 基因疗法是治疗肿瘤的新手段[1-2]。但目前面临的主要障碍是缺乏合适的基因治疗载体[3-4]。由于病毒性基因载体存在导向性差、携带能力低、免疫原性和潜在致瘤性等缺点[5]。因此,针对其缺点研制非病毒载体近来成为研究的热点,主要包括真核细胞表达质粒载体。
出处 《中国癌症杂志》 CAS CSCD 北大核心 2011年第6期495-498,共4页 China Oncology
基金 上海市科学技术委员会(No:1052nm05900) 上海市科学技术委员会(No:10ZR1428900)
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参考文献15

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共引文献17

同被引文献43

  • 1徐淑芳,徐咏梅,陈建钢.壳聚糖季铵盐纳米粒子的制备、表征及其缓释蛋白质药物性能[J].武汉大学学报(理学版),2004,50(6):721-725. 被引量:10
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