期刊文献+

慢性阻塞性肺疾病气道炎症的研究进展 被引量:58

下载PDF
导出
摘要 慢性阻塞性肺疾病(COPD)是一种气流受限呈不完全可逆和进行性发展状态的气道阻塞性肺部疾病,包括肺气肿、末梢气道疾病和慢性支气管炎。其发病机制尚未完全阐明,目前普遍认为COPD以气道、肺实质和肺血管的慢性炎症为特征,在肺的不同部位有肺泡巨噬细胞。
出处 《中国呼吸与危重监护杂志》 CAS 2011年第2期196-199,共4页 Chinese Journal of Respiratory and Critical Care Medicine
基金 国家自然科学基金(编号:81070034)
  • 相关文献

参考文献40

  • 1Elizabeth Sapey,Ali Ahmad,Darren Bayley,Paul Newbold,Noel Snell,Paul Rugman,Robert A. Stockley.Imbalances Between Interleukin-1 and Tumor Necrosis Factor Agonists and Antagonists in Stable COPD[J]. Journal of Clinical Immunology . 2009 (4)
  • 2Gorska K,Krenke R,Domagala-Kulawik J,et al.Comparison ofcellular and biochemical markers of airway inflammation in patientswith mild-to-moderate asthma and chronic obstructive pulmonarydisease:an induced sputum and bronchoalveolar lavage fluid study. Journal of Physiology and Pharmacology . 2008
  • 3Kim V,Kelemen SE,Abuel-Haija M,et al.Small airway mucousmetaplasia and inflammation in chronic obstructive pulmonarydisease. COPD Journal of Chronic Obstructive Pulmonary Disease . 2008
  • 4Tsuda Y,Noguchi T,Mochizuki H,et al.Patients with mild-to-moderate asthma may develop clinically significant chronicobstructive pulmonary disease. Respirology . 2009
  • 5Louhelainen N,Rytila P,Haahtela T,et al.Persistence of oxidantand protease burden in the airways after smoking cessation. BMCPulm Med . 2009
  • 6Corhay JL,Henket M,Nguyen D,et al.Leukotriene B4 contributesto exhaled breath condensate and sputum neutrophil chemotaxis inCOPD. Chest . 2009
  • 7Bartoli ML,Di Franco A,Vagaggini B,et al.Biological markers ininduced sputum of patients with different phenotypes of chronicairway obstruction. Respiration . 2009
  • 8Bafadhel M,Saha S,Siva R,et al.Sputum IL-5 concentration isassociated with a sputum eosinophilia and attenuated bycorticosteroid therapy in COPD. Respiration . 2009
  • 9Sarir H,Henricks PA,van Houwelingen AH,et al.Cells,mediatorsand Toll-like receptors in COPD. European Journal of Pharmacology . 2008
  • 10Kelsen SG,Aksoy MO,Georgy M,et al.Lymphoid follicle cells inchronic obstructive pulmonary disease overexpress the chemokinereceptor CXCR3. American Journal of Respiratory and Critical Care Medicine . 2009

同被引文献566

引证文献58

二级引证文献405

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部