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抗癫痫药物致迟发过敏性药疹三例 被引量:3

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摘要 抗癫痫药物引起的药疹报道已屡见不鲜,卡马西平、奥卡西平作为一线抗癫痫药物是复杂部分性发作的首选。这两种药物均可引起药疹,重型药疹可引起严重的皮肤损害且伴肝肾等重要脏器的损害,甚至死亡。2000年我们曾报道了6例重型卡[1]
出处 《中华临床医师杂志(电子版)》 CAS 2011年第8期2483-2484,共2页 Chinese Journal of Clinicians(Electronic Edition)
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参考文献11

  • 1耿磊钰,刘玉玺.抗癫痫药物致皮肤超敏反应的机制研究进展[J].国际神经病学神经外科学杂志,2005,32(6):498-500. 被引量:1
  • 2程春雷,游雪甫.细胞色素P4503A研究进展[J].国外医药(抗生素分册),2004,25(3):124-127. 被引量:17
  • 3刘玉玺,张建斌,刘聪喜,徐家立.卡马西平高度敏感综合征六例临床特征与救治报告[J].中华神经科杂志,2003,36(3):182-182. 被引量:7
  • 4Hsieh KP,Lin YY,Cheng CL,et al.Novel mutations of CYP3A4 in Chinese. Drug Metabolism and Disposition . 2001
  • 5Martinez-parra C.duran-ferreras E,Mir-mercader J,et al.Anticon-vulsant hypersensitivity syndrome with severe repercussions in the skin andkidneys due to carbamazepine. Revue Neurologique . 2004
  • 6Pastor ME,,Rubert GM.Oxcarbazepine induced interstitialnephritis in a patient with drug hypersensitivity syndrome. Revue Neurologique . 2003
  • 7Mauri HD,,Bettens F,Mauri D,et al.Activation of drug-specific CD4+and CD8+Tcells inindividuals al-lergict to sulfonamides,phenyltoin and carbamazepine. JImmunol . 1995
  • 8Fritsch,P.O.,Sidoroff,A.Drug-induced Stevens-Johnson syndrome/toxic epidermal necrolysis. American Journal of Clinical Dermatology . 2000
  • 9Mockenhaupt M,Messenheimr J,Tennis P,et al.Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users ofantiepileptics. Neurology . 2005
  • 10S.R. Knowles,L.E. Shapiro,N.H. Shear.Anticonvulsant hypersensitivity syndrome: incidence, prevention and management. Drug Safety . 1999

二级参考文献35

  • 1Balley DG,Dresser GK,Kreeft JH,et al.Grapefrut-feledipine interaction:effect of unprocessed fruit and robable ingredients [J].Clin Pharmacol Ther,2000,68:468
  • 2Gegg CR.Drug interaction and anti-infective therapies[J].Am J Med,1999,106:227
  • 3Nelson DR,Koymans L,kamataki T,et al.P450 superfamily:update on new sequences,gen mapping,accession numbers and nomenclature[J].Pharmacogenetics,1996,6 (1):1
  • 4Drcss GK,Spence JD,Bailey DG.Pharmcokinetic-pharmacodynamic cousequences and clinical relevance of cytochrome P4503A4 inhibition [J].Clin Pharmacokenet,2000,38(1):41
  • 5Commins CL,Wu CY,Benet LZ.Sex-related differences in the clearance of cytochrome P4503A4 substrate maybe caused by Pglycoprotein[J].Clin Pharmacol Ther,2002,72 (5):474
  • 6Murray M,Cantrill E,Metha I,et al.Impaired expression of microsomal cytochrome P450 2C11 in choline-deficient rat liver during the development of cirrhosis[J].J Pharmacol Exp Ther,1992,261:373
  • 7Lytton SD,Helander A,Zhiang-Gouillon ZQ,et al.Autoantibodies against cytochrome P-4502E1 and P-4503A in alcoholics[J].Mol Pharmacol ,1999,55:223
  • 8Thummel KE,Shen DD,Podoll TD,et al.Use of midazolam as a human cytochrome P4503A probe:in vivo-in vitro correlation in liver trensplant patients[J].J Pharmaco Exp Ther ,1994,271:549
  • 9Iwahori T,Matsuura T,Maehashe H,et al.CYP3A4 inducible model for in vitro analysis of human drug metabolism using a bioartifical liver[ J ].Hepatology,2003,37(3):665
  • 10Gibson GG,Plant NJ,Swales KE,et al.Receptor-dependent transcriptional activation of P4503A genes:Inducation Mechanism,Species differences and interindividnal variation in man [J].Xenobiotica,2002,32 (3):165

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