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白细胞介素8与胃癌的研究进展 被引量:1

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摘要 胃癌是一类严重威胁人类健康的疾病,是全世界第四位常见恶性肿瘤,位居肿瘤相关死亡率的第二位[1]。全世界每年有90万新发胃癌病例,70万胃癌相关的死亡发生[2]。在我国,胃癌更是一种高发疾病,治疗困难,预后不佳。
出处 《中华临床医师杂志(电子版)》 CAS 2011年第9期2666-2668,共3页 Chinese Journal of Clinicians(Electronic Edition)
基金 国家自然基金重大研究计划面上项目(90709044)
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参考文献3

  • 1AS Haqqani,JK Sandhu,HC Birnboim.Expression of interleukin-8 promotes neutrophil infiltration and genetic instability in mutatect tumors. Neoplasia . 2000
  • 2SINGH R K,LOKESHWAR B L.Depletion of intrinsic expression of Interleukin-8in prostate cancer cells causes cell cycle arrest,spontaneous apoptosis and increases the efficacy of chemotherapeu-tic drugs. Molecular Cancer . 2009
  • 3Yamada H,Aihara T,Okabe S.Mechanism for Helicobacter pylori stimulation of interleukin-8 production in a gastric epithelial cell line (MKN28):roles of mitogen activated protein kinase and interleukin-1 beta. Biochemical Pharmacology . 2001

同被引文献13

  • 1刘福囝,滕勇,张晓旭,黎瀚,刘璐,孙瑞佳,徐惠绵.miR-210在胃癌组织中的表达及临床意义[J].中华临床医师杂志(电子版),2011,5(9):2701-2703. 被引量:5
  • 2Kong C,Wang C,Wang L. Huang BNEDD9 is a positive regulator of epithelial-nesenchymal transition and promotes invasion in aggressive breast cancer[J].PLoS One,2011.e22666.doi:10.1371/journal.pone.0022666.
  • 3Natarajan M,Stewart JE,Golemis EA. HEFI is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells[J].Oncogene,2006.1721-1732.
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  • 6Kumar S,Tomooka Y,Noda M. Identification of a set of genes with developmentally down-regulated expression in the mouse brain[J].Biochemical and Biophysical Research Communications,1992.1155-1161.
  • 7Tikhmyanova N,Golemis EA. NEDD9 and BCARI Negatively Regulate.E-Cadherin Membrane Localization,and Promote E-Cadherin degradation[J].PLoS One,2011.e22102.doi:10.1371/journal.pone.0022102.
  • 8Li Y,Bavarva JH,Wang Z. HEF1,a novel target of Wnt signaling,promotes colonic cell migration and cancer progression[J].Oncogene,2011.2633-2643.
  • 9Izumchenko E,Singh MK,Plotnikova OV. NEDD9 Promotes Oncogenic Signaling in Mammary Tumor Development[J].Cancer Research,2009.7198-7206.
  • 10Law SF,Estojak J,Wang B. Human enhancer of filamentation l,a novel p130cas-like docking protein,associates with focal adhesion k inase and induces pseudohyphal growth in Saccharomyces cerevisiae[J].Molecular and Cellular Biology,1996.3327-3337.

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