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发作性睡病四例

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摘要 发作性睡病(narcolepsy)是一种发病机制尚未清楚的睡眠障碍性疾病。在西方的大多数研究中其患病率为167~799/10万人,在日本其患病率比较高,为1600/10万人[1-2],中国香港的一项研究报告表明,在香港该病的患病率为340/10万人[3]。
出处 《中华临床医师杂志(电子版)》 CAS 2011年第9期2783-2784,共2页 Chinese Journal of Clinicians(Electronic Edition)
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参考文献10

  • 1凌明.莫达非尼的临床应用[J].现代医药卫生,2007,23(17):2661-2661. 被引量:3
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  • 3Coelho FM,Pradella-Hallinan M,Alves GR,et al.Report of two narcoleptic patients with remission of hypersomnolence following use of prednisone. Arquivos de Neuropsiquiatria . 2007
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  • 10Wing YK,Li RH,Lam CW,et al.The prevalence of narcolepsy among Chinese in Hong Kong. Annals of Neurology . 2002

二级参考文献6

  • 1Chariot J,Appia F,Vaille c,et al.Effect of modafinil on pancreatic excrine secretion in rate:a comparison with adrafinil and related drugs[J].Fundam Clin Pharmacol,1987,1(4):243.
  • 2Wong YN,King SP,Simcoe D,et al.Open-label,single-dose pharmacokinetic study of modafinil tablets:influence of age and gender in normal subjects[J].J Clin Pharmacol,1999,39(3):281.
  • 3Hellriegel ET,Arora S,Nelson M,et al.Steady-state pharmacokdnetics and tolerability of modafinil given alone or in combination with dextroamphetamine in healthy volunteers[J].J Clin Pharmacol,2001,42(4):450.
  • 4US Modafinil in Narcolepsy Multicenter Study Group.Randomized trial of modafinil as a treat ment for the excessive daytime somnolence of narcolepsy[J].Neurology,2000,54(5):1 166.
  • 5Wong YN,Simcoe D,Hartman LN,et al.A double-blind,placebocontrolled,ascending dose evaluation of the pharmacokinetics and tolerability of modafinil tablets in healthy male volunteers[J].J Clin Pharmacol,1999,39(1):30.
  • 6Heitmann J,Csssel W,Grote L,et al.Does short-term treatment with modafinil affect blood pressure in patients with obstrutive sleep apnea[J].Clin Pharmacol Ther,1999,65(3):328.

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