期刊文献+

膀胱癌高表达基因BCA7的表达分析 被引量:2

原文传递
导出
摘要 目的筛选膀胱癌高表达基因。方法通过生物信息学筛选,获得候选膀胱癌高表达基因,然后通过RT-PCR进行验证,确定膀胱癌高表达基因。结果通过生物信息学对人类基因组超过50000个基因进行筛选,得出候选基因,然后进行RT-PCR验证,发现BCA7的mRNA在膀胱癌组织表达明显高于癌旁正常组织,且在全身其他正常组织中基本没有表达。结论 BCA7基因为膀胱癌高表达基因,可能在膀胱癌发生、发展及在膀胱癌早期诊断、术后监测中起重要作用。
出处 《中华临床医师杂志(电子版)》 CAS 2011年第11期3299-3301,共3页 Chinese Journal of Clinicians(Electronic Edition)
  • 相关文献

参考文献3

  • 1Gutiérrez Baos JL,del Henar Rebollo Rodrigo M,Antolín Juárez FM,et al.Usefulness of the BTA STAT Test for the diagnosis of bladder cancer. Urology . 2001
  • 2Seracchioli R,Mannini D,Colombo FM,et al.Cystoscopy-assisted laparoscopic resection of extramucosal bladder endometriosis. . 2002
  • 3许斌(综述),华立新(审校).膀胱癌流行病学进展[J].国际泌尿系统杂志,2007,27(4):469-476. 被引量:14

二级参考文献28

  • 1Mohr DN, Offord KP, Owen RA,et al. Asymptomatic microhematuria and urologic disease: a population -based study. JAMA, 1986, 256: 224 - 229.
  • 2Murphy WM : Urinary Cytopathology. Chicago, ASCP Press, 2000.
  • 3Mulders PFA, Meyden APVD, Doesburg WH, et al.fur the Dutch Southeastern Urological Collaborative Group. Prognostic factors in pT1 - pT1 superficial bladder tumors treated with intra vesical instillations. Br J Urol,1994,73:403 -408.
  • 4Pagano F, Garbeglio A, Milani C, et al. Prognosis of bladder cancer. I. Risk factors in superficial transitional cell carcinoma. Eur Urol, 1987,13 : 145 - 149.
  • 5Grimm MO, Steinhoff C, Simon X, et al. Effect of routine repeat transurethral resection for superficial bladder cancer: a long - term observational study. J Urol,2003,170 : 433 - 437.
  • 6Konety BR,et al. Clinical usefulness of the novel marker BLCA -4 for the detection of bladder cancer. J Uroi,2000,164(3 Pt 1) :634 - 639.
  • 7Giannopoulos A, et al. Comparative evaluation of the diagnostic performance of the BTA stat test, NMP22 and urinary bladder cancer antigen for primary and recurrent bladder tumors. J Urol,2001,166 (2) :470 -475.
  • 8Sylvester RJ, et al. Bacillus calmette - guerin versus chemotherapy for the intravesical treatment of patients with carcinoma in situ of the bladder: a meta - analysis of the published results of randomized clinical trials. J Urol,2005,174( 1 ):86-91.
  • 9Dan Leibovici, et al. Partial cystectomy for muscle invasive urothelial carcinoma of the bladder: a contemporary review of the M. D. Anderson Cancer Center experience. J Urol, 2006, 175 ( 6 ) : 2058 - 2062.
  • 10Honma l, Masumori N,et al. Removal of more lymph nodes may provide better outcome, as well as more accurate pathologic findings, in patients with bladder cancer - - analysis of role of pelvic lymph node dissection. Urology,2006,68(3) :543 -548.

共引文献13

同被引文献20

  • 1许斌(综述),华立新(审校).膀胱癌流行病学进展[J].国际泌尿系统杂志,2007,27(4):469-476. 被引量:14
  • 2RAITANEN M P. The role of BTA stat Test in fol- low-up of patients with bladder cancer: results from FinnBladder studies[J]. World J Urol, 2008,26.. 45 -50.
  • 3SERACCHIOLI R, MANNINI D, COLOMBO F M, et al. Cystosoopy-assisted laparoscopic resection of extramucosal bladder endometriosis[J]. J Endourol, gOO2,16 : 663 - 666.
  • 4BARLANDAS-RENDON E, MULLER M M, GAR- CIA-LATORRE E, Heinschink A. Comparison of u- rine cell characteristics by flow eytometry and eytolo- gy in patients suspected of having bladder caneer[J]. Clin Chem Lab.Med, 2002,40: 817-823.
  • 5EGGENER S, HERR H. NMP22 and surveillance for recurrent bladder cancer[J]. JAMA, 2006,296: 45.
  • 6KAPILA K, KEHINDE E O, ANIM J T, et al. Could nuclear matrix protein 22 (NMP22) play a role with urine cytology in screening for bladder cancer? - experience at Kuwait University[J]. Cytopathology, 2008, 19:369-374.
  • 7Ploeg M, Aben KK, Kiemeney LA, et al. The present and future burden of urinary bladder cancer in the world[J]. World J Urol,2009,27(3) :289-293.
  • 8Jacobs BL, Lee CT, Montie JE. Bladder cancer in 2010: how far have we come? [J]. CA Cancer J Clin,2010,60(4) :244- 272.
  • 9Raghavan D, Shipley WU, Gamick MB, et al. Biology and management of bladder cancer[J]. N Engl J Med, 1990,322 (16):1129-1138.
  • 10Sternberg CN. The treatment of advanced bladder cancer[J]. Ann Onco1,1995,6(2) :113-126.

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部