中成药乳疾消胶囊的显微鉴别研究

Microscopic Identification of Ru Ji Xiao Capsules

目的:对乳疾消胶囊中温郁金、蓬莪术、北柴胡、丹参、黑三棱五味以原粉入药的中药材进行定性鉴别。方法:借助于生物显微镜,鉴别乳疾消胶囊中蓬莪术、北柴胡、丹参、黑三棱药材;以糊化淀粉粒团块为显微特征物,采用容量分析与显微定量相结合的方法对乳疾消胶囊中的温郁金进行定性鉴别。结果:确定了乳疾消胶囊中蓬莪术、北柴胡、丹参、黑三棱药材的显微鉴别特征分别为非腺毛、油管碎片、石细胞、淀粉粒;在此基础上,当每毫克乳疾消胶囊中所含糊化淀粉粒团块数为29.70～37.58个时,证明制剂中同时存在温郁金药材。结论:乳疾消胶囊处方组成中温郁金、蓬莪术、北柴胡、丹参、黑三棱五味药材的显微鉴别方法简便可靠,对环境污染较小,为该制剂的质量控制提供了可资借鉴的依据。

Objective:To identify five Chinese medicinal herbs,Radix Curcumae,Rhizoma Curcumae,Radix Bupleuri,Radix Salviae Miltiorrhizae and Rhizoma Sparganii in Ru Ji Xiao Capsules.Methods:The Rhizoma Curcumae,Radix Bupleuri,Radix Salviae Miltiorrhizae and Rhizoma Sparganii in Ru Ji Xiao Capsules were identified with biological microscope;The Radix Curcumae in Ru Ji Xiao Capsules was determined with the methods of volumetric analysis combined with microscopic quantitation according to the microscopic character,gelatinizing bolus of starch granule.Results:The microscopic features of Rhizoma Curcumae,Radix Bupleuri,Radix Salviae Miltiorrhizae and Rhizoma Sparganii were nonglandular hairs,fragments of oil ducts,grit cells,starch grains,respectively;When the number of gelatinizing bolus of starch granules ranged from 29.7～37.58,which showed that Radix Curcumae and other four herbs contained in the Ru Ji Xiao Capsules.Conclusion:The experiment showed that the method for identifying Radix Curcumae,Rhizoma Curcumae,Radix Bupleuri,Radix Salviae Miltiorrhizae and Rhizoma Sparganii in Ru Ji Xiao Capsules was reliable,convenient and with the benefit of less environmental contamination,which supplies the evidence to control the quality of the capsules.