反相悬浮—化学交联法制备聚乙烯醇交联微球CPVA

Preparation of Crosslinked Mircospheres of CPVA with Inverse Suspension-Chemical Crosslinking Method

以聚乙烯醇(PVA)为单体,戊二醛(GA)为交联剂,山梨醇酐单硬脂酸酯(span60)为分散剂,采用反相悬浮-化学交联法,制备了聚乙烯醇交联微球CPVA.采用FT-IR和sEM对其化学结构和微观形貌进行了表征,考察了搅拌速率、交联剂的用量、催化剂(盐酸)的用量对交联微球的成球性能及粒度的影响规律。结果表明,在反相悬浮体系中,搅拌速度、交联剂的用量是影响交联微球制备的主要因素,当搅拌速度小于250r/min、交联剂的用量大于2ml时,体系中均不能成球。在体系中加入盐酸后,交联微球的粒径随盐酸用量的增大而增大。控制成球的反应条件可以制备出球形度良好、粒径在150μm左右的粒径可控的聚乙烯醇交联微球CPVA。

CPVA was performed with Inverse Suspension-Chemical Crosslinking Method by using polyvinyl alcohol (PVA) as monomer,glutaraldehyde(GA) as crosslinker and Span60 as disperser.The chemical structure and morphology were characterized with infrared spectrum(FTIR) and scanning electron microscope(SEM) respectively.Effects of various factors such as stirring speed,content of crosslinker and hydrochloric acid,on the sphericity and size of microspheres were examined. The experimental results show that the first two factors are key factors.As the the stirring rate is lower than 250r/min,content of crosslinker is more than 2ml,balling process can not be realized in the system.The size of microspheres increases with increasing the added amount of hydrochloric acid.Via controlling the reaction conditions,the crosslinked microspheres CPVA with excellent sphericity and controllable particle diameter around 150μm can be gained.