盐酸多西环素滴丸抗老化研究

Study on Antiageing of Doxycycline Hydrochloride Dropping Pills

目的:对盐酸多西环素滴丸进行抗老化研究。方法:由紫外、液相、X-射线衍射、电镜扫描对比图判断盐酸多西环素滴丸的老化原因,并提出解决方案。结果:盐酸多西环素滴丸的老化是由杂质的引入造成,通过加入抗氧剂Vc使老化问题得到解决。结论:处方中加入Vc制备的盐酸多西环素滴丸化学性质稳定,Vc抗老化作用明显。

Objective:To study on antiageing of doxycycline hydrochloride dropping pills.Methods:Using UV,HPLC,X -ray diffraction and electron microscope scanning,the reasons induced antiageing of doxycycline hydrochloride dropping pills were found and the solving scheme was proposed.Results:The impurity were input to cause antiageing of doxycycline hydrochloride dropping pills and the problem can be solved by using antioxidant Vc.Conclusion:Doxycycline hydrochloride dropping pills were more stable through adding in antioxidant Vc and the Antiageing effect of Vc is significant.