健脾升白合剂升高白细胞作用研究

Study on Efficacy of Jianpishengbai Mixture for Raising the Leukocyte

目的:观察健脾升白合剂对化疗引起的白细胞减少症的预防和治疗作用。方法:以环磷酰胺腹腔注射造成小鼠白细胞减少症模型,用健脾升白合剂进行治疗,对模型小鼠外周血象和骨髓造血功能进行检测。结果:健脾升白合剂可明显对抗模型小鼠的白细胞减少。结论:健脾升白合剂可保护小鼠外周血中白细胞免受环磷酰胺的伤害,同时对白细胞的提高有一定的促进作用。

Objective:To study the effect of Jianpishengbai mixture on the leukopenia in chemotherapeutic damage mice.Methods:Cyclophosphamide were administered intraperitoneally to mice to develop leukopenia,and the mice were treated with Jianpishengbai mixture.The number of peripheral leukocytes and bone marrow cells of all the sacrificed animals were examined.Results:Jianpishengbai mixture markedly raise peripheral blood leukocytes and marrow karyocytes in the mice model of leukopenia.Conclusion:Jianpishengbai mixture could protect mice against chemotherpeutic damaged by cyclophosphamide and raise peripheral blood leukocyte.