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昔布类药物的临床安全性研究 被引量：1

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摘要 目的:评价昔布类药物的临床安全性。方法:综述近年来国内外关于昔布类药物临床安全性的文献与报道,分别对全球已上市的六种昔布类药物进行安全性评价。结果:昔布类药物有增加心血管事件的风险,但它们的类效应强度不同,合理选择使用利大于弊。
作者 孙禹威 金文成
机构地区 哈尔滨市第一医院药剂科
出处 《黑龙江医药》 CAS 2009年第6期875-876,共2页 Heilongjiang Medicine journal
关键词 昔布 COX-2抑制剂 安全性
分类号 R969.3 [医药卫生—药理学] R971+1 [医药卫生—药品]
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参考文献8

二级参考文献33

  • 1FDA announces a series of changes to the class of marketed non-steroidal anti-inflammatory drugs (NSAIDs). www. fda.gov/bbs/topics/news/2005/NEW01171. html , 2005-04-07/2005 -05.
  • 2COX-2 Selective and Non-Selective Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). www. fda. gov/cder/drug/infopage/ COX2/ default. htm ,2005-04-07/2005-05.
  • 3Questions and Answers: FDA Regulatory Actions for the COX-2 Selective and Non-Selective Non-Steroidal Anti-inflammatory drugs ( NSAIDs ) . www. fda. gov/cder/drug/infopage/ COX2/ CO X2qa. htm ,2005-04-07/2005-05.
  • 4FDA Public Health Advisory: FDA Announces Important Changes and Additional Warnings for COX-2 Selective and Non-Selective Non-Steroidal Anti-Inflammatory Drugs(NSAIDs ). www. fda. gov/cder/drug/advisory/COX2. htm,2005 -04-07/2005 -05.
  • 5.国家食品药品监督管理局密切关注非甾体类抗炎药物的安全性问题[EB/OL].http://www.sfda.gov.cn/cmsweb/webportal/W1/search. html,2005-04-12/2005-05.
  • 6European Medicines Agency announces regulatory action on COX-2 inhibitors. http ://www. emea. eu. int/htms/hotpress/d6275705. htm, 2005-04-17/2005-05.
  • 7European Medicines Agency statement on the suspension of use of Bextra. http://www. emea. eu. int/htms/hotpress/h12163705. htm, 2005-04-12/2005-05.
  • 8Media Releases Stringent Conditions for COX-2 Inhibitors.http ://www. medsafe. govt. hz/hot/media/2005/COX2April05. htm, 2005-04 -29/2005-05.
  • 9Health Canada has asked Pfizer to suspend sales of its drug BextraTM and informs canadians of new restrictions on the use of Celebrex (R). http://www. hc-sc. gc. ca/english/media/releases/2005 / statement_drug_safety. html , 2005-04-07/2005-05.
  • 10Expanded information on Cox-2 inhibitors for doctors and pharmacists (amended * ). http://www. tga. gov. au/media/2005/050214_cox2. htm#pdf , 2005-04-14/2005-05.

共引文献31

同被引文献17

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引证文献1

二级引证文献5

黑龙江医药
2009年 第6期

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