摘要
目的探讨抑郁症患者脑诱发电位(P300)变化与自杀行为的关系。方法应用国产脑诱发电位仪,记录了48例抑郁症患者和40名正常对照者的P300。结果与正常对照组相比,抑郁症组均出现P300主成分波幅降低,抑郁症组P3潜伏期延迟(P<0.01);抑郁症组的P300改变主要与有无自杀行为史有关。结论 P300变化与自杀行为的相关性需进一步追踪随访。
Objective To investigate the relevance of brain evoked potential(P300) change and suicidal behavior in patients with depression.Methods Forty-eight depressed patients and 40 normal controls were chosen and their brain evoked potential(P300) were recorded,using a Chinese instrument.Results Depressed patients had prolonged latencies and decreased amplitudes of major components of P300 as compared with the normal controls(P<0.01).The changes of P300 were related to the history of suicidal behavior in depressed patients.ConclusionThe possible relationship between P300 changes and suicidal behavior needs to be further studied.
出处
《神经病学与神经康复学杂志》
2010年第2期78-80,共3页
Journal of Neurology and Neurorehabilitation
基金
金华市科学技术局资助项目(2009-3-059)
关键词
抑郁症
脑诱发电位
自杀行为
depression
brain evoked potentials
suicidal behavior