摘要
目的为难治性癫(IE)患者的外科治疗制定循证方案。方法针对1例IE患者诊治中的临床问题,检索临床指南、系统评价、m eta分析及随机对照试验,并评价其质量,判断其真实性、适用性,获取最佳证据并应用于临床。结果共检索到3篇指南、5篇系统评价和1篇结局研究,分析结果表明IE从定义到诊治都还存在着许多争议。结合患者情况,应用循证证据治疗,随访半年的疗效较好。结论循证治疗可以提高患者疗效,但仍然缺乏充分的证据。
Objective To formulate an evidence-based surgical treatment plan for a patient with intractable epilepsy(IE).Methods For the diagnosis and treatment of clinical problem in one patient with IE,retrieval of clinical guidelines,systematic reviews,meta analysis and randomized controlled trials were carried out,and we also evaluated its quality,determined its authenticity,fitness,got the best evidence and clinical application.ResultsA total of three guides,five systematic reviews and one outcome research were included,and the analysis showed that there were still a lot of controversy from definition to treatment in IE.The efficacy is better after six month treatment by combined with patient's condition and treatment with evidence-based evidence.Conclusion Evidence-based treatment can improve patient outcomes,but still lack sufficient evidence.
出处
《神经病学与神经康复学杂志》
2010年第3期149-152,共4页
Journal of Neurology and Neurorehabilitation
关键词
难治性癫(癵)
循证
手术治疗
intractable epilepsy
evidence
surgical treatment
