GC-MS法检测化妆品中6种邻苯二甲酸酯

Determination of 6 kinds of phthalate acid esters in cosmetics by GC-MS

利用气相色谱-质谱联用(GC-MS)技术,对固态、半固态、液态化妆品中6种邻苯酸二甲酯类化合物(DMP、DEP、DBP、BBP、DEHP、DNOP)进行检测。样品经甲醇提取、无水硫酸钠脱水后上机检测,检测方法的检出限为0.2mg/kg,平均回收率为71.7%～109.0%,平均相对标准偏差(RSD)1.57%～4.53%。该方法能够满足各种化妆品中6种邻苯二甲酸酯检测的需要。

Gas chromatography-mass spectrometry(GC-MS) technology was used to detect six kinds of phthalic acid esters(DMP,DEP,DBP,BBP,DEHP,DNOP) in the solid,semi-solid and liquid of cosmetics.The sample was detected after extraction by methyl alcohol and dehydration by anhydrous sodium sulfate,in which the method detection limit was 0.2 mg/kg,the average recovery was 71.7% to 109.0%,the average relative standard deviation(RSD) was 1.57%-4.53%.The method can meet detection of 6 phthalate esters in all kinds of cosmetics.