脑脉通化学成分的研究(Ⅰ)

A Study of Chemical Constituents from NaoMaiTong(Ⅰ)

采用色谱法对中药复方脑脉通的化学成分进行分离,采用化学方法及现代波谱技术对分离得到的化合物进行结构鉴定.分离得到10个化合物,分别鉴定为大黄酚,大黄素甲醚,2-甲氧基-6-乙酰基-7-甲基胡桃醌,大黄素,2,5-二甲基-7-羟基色原酮,芦荟大黄素,大黄酚甲醚,5-羟甲基糠醛,β-谷甾醇,胡萝卜苷.以上化合物均为首次自脑脉通复方中分离得到,其中化合物5-羟甲基糠醛为首次在组成脑脉通复方的4味中药中发现.

The chemical constituents of NaoMaiTong were isolated by chromatographic method,and structurally elucidated by their spectral data.Ten compounds were obtained and identified as chrysophanol,physcion,2-methoxy-6-acetyl-7-methyljuglone,emodin,2,5-dimethyl-7-hydroxychromone,aloeemodin,chrysophanol-8-Meether,5-hydroxymethyl-2-furancarboxaldehyde,β-sitosterol and daucosterol.Ten compounds are isolated from NaoMaiTong for the first time,and the 5-hydroxymethyl-2-furancarboxaldehyde is isolated from four traditional Chinese medicines which form NaoMaiTong for the first time.