摘要
Long-duration ventricular fibrillation (LDVF) often occurring out-of-hospital has been presented several minutes before electrical shocks. It is important to understand the mechanism by which LDVF is maintained and defibrillated. Purkinje fibers (PFs) have been demonstrated to play a key role in the onset of certain types of ventricular fibrillation. In this review, we discuss the electrophysiological difference between PFs and working myocardium, and the role of the PFs in the maintenance and termination of LDVF.
Long-duration ventricular fibrillation (LDVF) often occurring out-of-hospital has been presented several minutes before electrical shocks.It is important to understand the mechanism by which LDVF is maintained and defibrillated.Purkinje fibers (PFs) have been demonstrated to play a key role in the onset of certain types of ventricular fibrillation.In this review,we discuss the electrophysiological difference between PFs and working myocardium,and the role of the PFs in the maintenance and termination of LDVF.
基金
Supported by National Natural Science Foundation of China (81000081,81070266)
