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N-(4-羟基-L-脯氨酰基)-L-丝氨酸的合成 被引量:1

Synthesis of Dipeptide 4-Hydroxyl-L-Pro-L-Ser
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摘要 以N-叔丁氧羰基-O-苄基-L-丝氨酸和N-叔丁氧羰基-4-羟基-L-脯氨酸为原料,经由羟基保护,二环己基碳二亚胺(DCC)缩合,脱保护基等步骤合成了4-羟基-L-脯-L-丝二肽。 Here,total synthesis of 4-hydroxyl-L-Pro-L-Ser has been completed,it started from Boc-4-OH-Pro-OH and Boc-Ser(Bn)-OBn,which underwent hydroxyl protection,condensation with DCC and deprotection to gain the final product.
出处 《精细化工中间体》 CAS 2012年第2期36-37,共2页 Fine Chemical Intermediates
关键词 n-叔丁氧羰基-o-苄基-l-丝氨酸 n-叔丁氧羰基-4-羟基-l-脯氨酸 dcc缩合 Boc-4-OH-Pro-OH Boc-Ser(Bn)-Obn condensation with DCC
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