摘要
以苯酚、溴和4—硝基氯苯为合成主要原料,通过亲电取代和Williamson反应,合成了2,4,6-三溴-4'-硝基二苯醚。并通过IR、1H NMR和13C NMR对其结构进行了确证。进一步研究了反应温度、氢氧化钠用量、反应物的量比、回流时间对合成反应的影响,合成收率达到94.0%。
Phenol,bromine and 4-the main raw material for the synthesis of nitro-chlorobenzene,and Williamson by electrophilic substitution reaction,synthesis of 2,4,6-bromo-4 '-nitro-diphenyl ether,The structure 0f the product was confirmed by IR and 1H NMR and 13C NMR.Further study of the reaction temperature,sodium hydroxide,reaction molar ratio,reflux time on the synthesis reaction,synthesis yield of 94.0%.
