肾移植与腹膜透析患者生活质量比较的病例对照研究

Comparison of quality of life in renal transplantation and peritoneal dialysis patients:a case-control study

目的比较肾移植患者与腹膜透析患者的生活质量。方法采用病例对照的研究方法,以性别、年龄、文化程度、工作与否、付费方式、肾替代治疗时间作为匹配条件,选择肾移植和腹膜透析患者各58例,以健康相关生活质量问(Short Form 36 Health Survey Questionnaire,SF-36)评估其生活质量。结果肾移植与腹膜透析患者的生理综合得分和精神综合得分均无显著性差异,在涉及的8个维度中,肾移植患者的生理机能(t=3.060,P=0.003)、一般健康状况(t=2.579,P=0.011)和精力(t=2.610,P=0.011)高于腹膜透析患者,而生理职能(Z=3.917,P=0.000)低于腹膜透析患者。结论肾移植与腹膜透析患者总体生活质量无差异,仅个别维度有差异;良好的疾病管理能改善患者生活质量,应加强肾替代治疗患者的管理。

Objective To compare the quality of life between renal transplantation (RT) and peritoneal dialysis(PD) patients.Methods A case-control study was used,matching sex,age,education level,employment,means of payment and renal replacement therapy duration in two groups.58 pairs were selected to fill out Short Form 36 Health Survey Questionnaire(SF-36) which was used to evaluate their quality of life.Results There were no significant differences in physical component summary and mental component summary between two groups.Physical functioning (t=3.060,P=0.003),general health (t=2.579,P=0.011) and vitality (t=2.610,P= 0.011) of RT patients were higher than those of PD patients,whereas role-physical(Z=3.917,P=0.000) was lower than PD patients.Conclusions There was no significant difference in total quality of life between two groups.High-quality disease management would benefit to improve the quality of life.We should pay more attention to the disease management,especially for RT patients.