胃食管反流病治疗研究进展

Treatment of gastroesphageal reflux disease:An update

胃食管反流病(gastroesophageal reflux disease,GERD)由胃内容物反流引起不适症状和(或)并发症的一种疾病,其典型症状为:烧心、反酸、非心源性胸痛,其发病率在世界范围内呈逐年上升趋势,且随年龄增长而增加,40～60岁为发病高峰年龄。GERD治疗的目的是愈合食管炎,快速缓解症状、减少复发、提高生活质量。文中对近年GERD的治疗新进展组作一综述。

Gastroesophageal reflux disease(GERD) is characterized by the reflux of gastric content into the esophagus with or without histological changes.Its typical symptoms are heartburn,acid reflux,and non-cardiac chest pain.In the last few decades,the incidence of GERD has progressively increased worldwide,with the highest incidence in those aged 40-60 years.The treatment of GERD is to cure esophagitis,relieve symptoms and reduce recurrence.