3-溴-4-甲氧基苯胺的合成

Synthesis of 3-Bromo-4-methoxyaniline

用对氟硝基苯为原料,经N-溴代丁二酰亚胺溴代制得3-溴-4-氟硝基苯,经甲醇钠醚化制得3-溴-4-甲氧基硝基苯后,再经硫化钠还原制得3-溴-4-甲氧基苯胺,总收率约63%。

3-Bromo-4-methoxyaniline was synthesized from p-fluoronitrobenzene via bromination and etherification to give 3-bromo-4-methoxynitrobenzene,followed by reduction with an overall yield of about 63%.