农药制剂中皮肤接触致敏组分BIT的检测和控制

Determination and Control of Skin Sensitiser BIT for Pesticide Formulations

在实验的基础上,提出了一种农药制剂中BIT(1,2-苯并异噻唑啉-3-酮)的检测方法和BIT纯品定值的方法。该方法中,BIT纯品的定值,采用"气相色谱法+水分"相组合的杂质倒扣法及用差示扫描量热(DSC)法测定纯度,使标准品定值结果更接近真值。结果表明:该法的检测下限(LOQ):39.38ng/μL,线性相关系数r=0.99995,回收率:99.96%～102.7%,检测精度RSD:0.032%～2.043%。

As a result of a large number of study and experiment,we suggest a new method which is used to inspect the content of BIT(1,2-Benzisothiazolin-3-one) in pesticide formulating and determinate assay of pure material for BIT.This method which adapts differential analysis(i.e.,assay is determined by difference——100% minus(%water + %other impurities) and purity analysis by DSC enable.For this method,its' required detection limit(LOQ) is 39.38 ng/μL,its' coefficient is 0.99995,its' recoveries are 99.96%~102.7%,its' precisions(RSD) are 0.032%~2.043%.