老年期胃癌预后因素分析

Analysis of Prognostic Factors of Gastric Cancer in Old Age

目的探讨影响老年期胃癌患者预后的因素。方法应用单因素和多因素的分析方法,回顾性分析2004年3月—2011年1月间肿瘤内科收治的178例老年期胃癌患者临床资料。结果单因素分析结果显示性别、癌栓、肿瘤大小、腹膜转移、肝转移、肺转移、骨转移、CEA、病理类型、分化程度及癌组织中淋巴细胞浸润程度与患者的预后具有相关性。多因素分析显示癌栓、肿瘤大小、腹膜转移、肝转移、分化程度、病理类型及癌组织中淋巴细胞浸润程度是影响胃癌患者手术预后的相关因素。结论癌栓、肿瘤大小、腹膜转移、肝转移、分化程度、病理类型及癌组织中淋巴细胞浸润程度是影响胃癌患者预后的重要指标。

Objective To analyze the related factors affecting the prognosis of gastric cancer of gerontal patients.Methods The clinical characteristics and follow up data of 178 gerontal patients with gastric cancer treated from March 2004 to January 2011 in our hospital were retrospectively analyzed by univariate and multivariate methods.Results In the univariate analysis,sex,cancer embolus,tumor size,peritoneal metastases,hepatometastasis,lung metastasis,bone metastasis,CEA,differential status,pathological type,degree of lymphocyte invasion were related to the prognosis of gerontal patients with gastric cancer.Multivariate Cox model analysis showed that cancer embolus,tumor size,peritoneal metastases,hepatometastasis,differential status,pathological type and degree of lymphocyte invasion were the related factors for gerontal patients with gastric cancer.Conclusion Cancer embolus,tumor size,peritoneal metastases,hepatometastasis,differential status,pathological type and degree of lymphocyte invasion are important prognostic factors for gerontal patients with gastric cancer.