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心型脂肪酸结合蛋白的测定与左室重构的相关性研究 被引量:3

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摘要 目的 探讨心型脂肪酸结合蛋白与心肌梗死后左室重构的关系及对心血管事件预测的价值.方法 回顾性分析我院收治的120例急性心肌梗死患者的临床资料,对不同心型脂肪酸结合蛋白检测结果患者治疗后2~4周的左室舒张末前后径、左室射血分数以及治疗后1,3,6个月心血管意外的发生情况进行对比分析.结果 120例患者中,发病24h后心型脂肪酸结合蛋白(H-FABP)正常组患者69例,H-FABP增高组51例.所有患者于治疗后2~4周复查心脏彩超均出现心室重构,但H-FABP正常组患者左室舒张末前后径明显小于H-FABP增高组,而左室射血分数明显高于H-FABP增高组.两组患者住院期间及治疗后1个月心血管意外发生率比较,差异无统计学意义;而治疗后3,6个月H-FABP增高组患者心血管意外发生率均明显高于H-FABP正常组,差异有统计学意义.另外发生心血管意外患者发病24h后H-FABP平均值也明显高于其他患者.结论 H-FABP的检测不仅能对心肌梗死的进行早期诊断,在治疗过程中进行H-FABP监测对心肌梗死患者心室重构程度的评价及心血管事件的预测也具有重要的价值.
作者 索蒲霞
出处 《现代诊断与治疗》 CAS 2012年第5期423-425,共3页 Modern Diagnosis and Treatment
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同被引文献65

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