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空腹血糖水平对无糖尿病的急性冠脉综合征患者近期预后的影响

Effects of level of fasting blood glucose on the recent prognosis in Non-diabetic patients with acute coronary syndromes
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摘要 目的探讨入院空腹血糖水平对无糖尿病的急性冠脉综合征(ACS)患者近期预后的影响。方法对235例无糖尿病的急性冠脉综合征患者,根据其入院次日空腹血糖水平分为A、B、C 3个组,血糖水平分别为:≤6.1mmol/L、6.2~10.0mmol/L、≥10.0mmol/L。对所有患者的临床临床资料进行回顾性分析。结果 3组患者在年龄、性别、吸烟、高血压、高脂血症的发生率方面差异均无统计学意义(P>0.05);B组、C组的肾功能不全发生率和CK-MB、C-反应蛋白(CRP)水平均高于A组(P<0.05);B组、C组急性心肌梗死(AMI)、左室功能不全(LVF)、严重心律失常、心源性猝死的发生率高于A组(P<0.05);C组AMI、LVF、严重心律失常、心源性猝死的发生率高于B组(P<0.05)。结论入院空腹血糖增高使ACS患者近期不良预后发生率增加,临床应加强对ACS患者的血糖控制。 Objective To explore effects of level of fasting blood glucose on the recent prognosis in Non-diabetic patients with acute coronary syndromes.Methods Two hundred and thirty-five Non-diabetic patients with acute coronary syndromes were divided into 3 groups according to level of fasting blood glucose(A:≤ 6.1mmol/L,B:6.2~10.0mm/L,C:≥10.0mmol/L).Results There was not significant difference in age,gender and incidence of smoking,hypertension,hyperlipidemia between 3 groups(P>0.05),but there was significant difference in incidence of renal insufficiency,and in levels of C-reactive protein(CRP),creatine kinase(CK-MB)(P<0.05).The incidence of acute myocardial infarction(AMI),left ventricular function failure(LVF),severe arrhythmia and cardiogenic sudden death were significantly higher in groups B,C than in group A(P<0.05),and higher in group C than in group B.Conclusion With rising of level of fasting blood glucose in patients with acute coronary syndrome,the incidence rate of ill prognosis is increased,and hyperglycemia of patients with acute coronary syndrome should be strictly controlled.
出处 《四川医学》 CAS 2012年第11期2002-2004,共3页 Sichuan Medical Journal
关键词 高血糖症 急性冠脉综合征 预后 hyperglycemia acute coronary syndrome prognosis
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参考文献5

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