期刊文献+

帕瑞昔布对多发骨折术后镇痛效果观察

下载PDF
导出
摘要 目的:目的:观察帕瑞昔布对多发骨折术后围手术期患者术后镇痛的效果。方法:选取2009年1月~2011年12月住院手术患者,共70例,随机分为治疗组和对照组,每组均为40例。治疗组术后连续三天均给予帕瑞昔布(40mg,bid)静脉推注,对照组不给予帕瑞昔布,两组在手术后不限制使用哌替啶镇痛药物。观察两组术后患者疼痛情况及哌替啶的用药情况,作统计学处理。结果:治疗组在术后3天手术切口疼痛的VAS评分、使用哌替啶的例数均低于对照组,差异有统计学意义。结论:静脉推注帕瑞昔布对多发骨折术后镇痛效果良好,能提高患者术后疼痛阈值,减少术后阿片类镇痛药的使用和不良反应,可临床推广。
作者 王荣滨
出处 《黑龙江医药》 CAS 2012年第5期729-730,共2页 Heilongjiang Medicine journal
  • 相关文献

参考文献3

  • 1郝永强,干耀恺,朱振安.塞来昔布对骨科围手术期镇痛的疗效评估[J].中国矫形外科杂志,2007,15(2):131-133. 被引量:28
  • 2R Subramaniam,C Joshi,A Sharma. Analgesic efficacy of single-dose parecoxib for corneal suturing in children[J].European Journal of Anaesthesiology,2007,(5):464-475.doi:10.1017/S0265021506001426.
  • 3Suners KA,Shaw BA,Gerardi JA. Comparison of morphine patient-controlled analgesia with and without ketorolac for poetoperative analgesia in pediatric orthopedic surgery[J].American Journal of Orthopedics,1999.351.

二级参考文献10

  • 1American Pain Society Quality Improvement Committee[S].JAMA.1995,1847-1880.
  • 2Joint Commission on Acchreditation of Healthcare Organizations[S].Jt Comm Perspect,1999,19(5):6 -8.
  • 3Stephens J,Laskin B,Pashos C,et al.The burden of acute postoperative pain and the potential role of the COX-2-specific inhibitors[J].Rheumatology (Oxford),2003,42 (3):40-52.
  • 4Romsing J,Moiniche S.A systematic review of COX-2 inhibiturs compared with traditional NSAIDs,or different COX-2 inhibitors for post-operative pain[J].Acta Anaesthesiol Scand,2004,48 (5):525-546.
  • 5Silverstein FE,Faich G,Goldstein JL,et al.Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis:the CLASS study:a randomized controlled trial:celecoxib long-term arthritis safety study[J].JAMA,2000,284:1247-1255.
  • 6Muhammad M,Paula AR,David NJ,et al.Observational study of upper gastrointestinal haemorrhage in elderly patients given selective cyclo ~ oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs[J].BM J,2002,325:624-627.
  • 7Silverstein FE,Faich G,Goldstein JL,et al.Gastrointestinal toxicity with Celecoxib vs nonsteroidal anti-inflammatory drugs for osteoasthritis and rheumatoid arthritis.The CLASS study:a randomized controlled trial[J].JAMA,2000,284:1247-1255.
  • 8Ekman EF,Fiechtner JJ,Levy S,et al.Efficacy of celecoxib versus ibuprofen in the treatment of acute pain:a multicenter,doubleblind,randomized controlled trial in acute ankle sprain[J].Am J Orthop,2002,31 (8):445 -451.
  • 9Gimbel JS,Brugger A,Zhao W,et al.Efficacy and toleraability of celecoxib versus hydrocodone/acetaminophen in the treatment of pain after ambulatory orthopedic surgery in adults[J].Clinical Therapeutics,2001,2:23.
  • 10Reuben SS,Ekman EF,Raghunathan K,et al.The effect of cyclooxygenase-2 inhibition on acute and chronic donor-site pain after spinalfusion surgery[J].Reg Anesth Pain Med,2006,31 (1):6-13.

共引文献27

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部