提高丙二酸二甲酯收率的实验研究

Improve the malonic acid methyl ester two experimental study

本文主要是通过改进的氰化酯化法来制备丙二酸二甲酯的实验研究,来探索提高丙二酸二甲酯收率的因素及其最佳工艺的参数。实验着重分析研究了氰化过程中的P^H值、反应时间和反应温度,酯化反应过程中的酸化液中水分含量、甲醇和氯乙酸的摩尔比、反应时间等过程因素对制备丙二酸二甲酯收率的影响。实验结果显示,改进的氰化酯化法制备丙二酸二甲酯的收率达到了85%以上,产品纯度在99%以上。

This paper is mainly through the improvement of the cyanide esterification method to prepare methyl malonic acid two experimental research,to improve two methyl malonic acid yield factors and optimal technological parameters.Experimental analysis of cyanide process pH value, reaction time and reaction temperature;esterification reaction in the process of acidification liquid water content,molar ratio of methanol and acetic acid,reaction time and process factors on the preparation of two methyl malonic acid yield.The experimental results show the improved cyanide was synthesized malonic acid two ester yield over 85%,the purity of the product in 99%above.