颈动脉粥样斑块与血浆C反应蛋白水平关系探讨

Clinical Study on Correlation between C-reactive Protein and Unstable Plaques of Carotid Atherosclerosis in Ischemic Cerebrovascular Patients

目的 探讨脑血管病人颈动脉粥样硬化斑块不稳定性与血浆CRP水平的关系。方法 将 1 1 2例缺血性脑血管病人按颈动脉超声表现分为三组 :颈动脉正常组、稳定型斑块组、不稳定斑块组 ;比较三组病人颅脑CT平扫颈内动脉分布区梗死灶计数 ;分别比较三组病人的血浆CRP水平。结果 三组病人上述指标间的差异经统计学处理均有显著性。结论 炎症与颈动脉粥样硬化的发生及斑块不稳定性成正相关 ;

Objective To explore the correlation between c-reactive protein and unstable plaques of carotid atherosclerosis in ischemic cerebrovascular patients.Methods 112 cases are divided into 3 groups according to their carotid ultrasonic examination:normal,stable plaque,unstable plaque;compare their plasma CRP concentrations and compare their infarction countings by CT.Results There is significant difference in their plasma CRP concentration between the three groups.Conclusion There's a positive relationship between inflammation and unstable plaques of carotid atherosclerosis in ischemic cerebrovascular diseases.CRP can be prediction to the instability of carotid atherosclerosis.