细胞移植在自体脂肪填充中的应用进展

Regenerative Cell Therapy in Autologous Fat Transfer

脂肪移植广泛应用于软组织的充填,但是其局部存活率不稳定的问题一直未能得到有效解决。越来越多的证据表明,各类间充质干细胞、血小板能够通过多种机制促进缺血组织新血管的生成,对促进移植脂肪的存活具有一定的作用。在脂肪移植中应用细胞辅助移植可以提高远期疗效,降低移植后脂肪组织液化吸收,减少局部并发症的发生。

Autologous lipo-transfer has been widely used in soft tissue implantation,yet its clinical application has the problem of instability of local survival rate.Recent data demonstrated that varies types of stem cells and platelets may promote the formation of new blood vessels of ischemia tissue through a variety of mechanisms.It plays an important role in promoting the survival of fat tissue and reducing the local atrophy of fat transplantation.Application of cell therapy in autologous lipo-transfer could enhance long-term outcomes,avoid absorption of adipose tissue after transplantation and reduce local complications.