西安地区乙肝病毒和丙肝病毒的感染现状

Epidemiological status of HBV and HCV infection in Xi'an area

目的调查西安地区当前乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)的流行状况。方法酶联免疫吸附法(ELISA)检测血清标本的乙型肝炎病毒血清标志物(HBV-M)六项及丙型肝炎病毒抗体,用PCR-荧光探针法检测丙型肝炎病毒核酸。结果人群HBV总阳性率64.6748%,HBsAg阳性率12.6753%,单独抗-HBs阳性率37.1672%,总抗-HBs阳性率48.8042%。抗HCV阳性率1.9159%,男性1.8486%,女性1.9823%。结论乙肝疫苗接种取得了较好的预防效应,但仍存在大量易感人群。HBV携带者阳性率12.6926%,高于以往文献报道的8%,乙型肝炎的防治工作仍需进一步加强。抗HCV阳性率1.9159%,低于以往报道的3%,阳性人群主要是>40岁中老年。

Objective To research the epidemiological status of HBV and HCV infection in Xian area.Methods Samples were tested for HBV-M (HBsAg,抗-HBs,HBeAg,抗-HBe,抗-HBc,HBcAb-IgM) and anti-HCV by ELISA,HCV-RNA was tested by fluorescent quantitative PCR.Results The total HBV positive rate is 64.6748%,HBsAg positive rate is 12.6753%,anti-HBs positive rate is 37.1672%,the total anti-HBs positive rate is 48.8042%. anti-HCV positive rate is 1.9159%,and 1.8486%for men and 1.9823%for women.Conclusion Inoculating Hepatitis B vaccine has good prevention effect; positive rate of HBV carrier is 12.6926%higher than 8%from previous reports;the prevention and control of HBV has need to be further strengthened. Anti-HCV positive rate is 1.9159%lower than 3%of the previous reports;and positive people is mainly over 40 years old.