摘要
长期以来,人们对维生素D的认识主要集中在对钙磷骨代谢的调节。自1980年,人们在钙磷骨代谢相关细胞外,如甲状旁腺细胞、淋巴细胞、胸腺及前髓细胞等发现了维生素D受体后,对维生素D的认识进一步开阔,后期的研究结果显示维生素D除了调节钙磷骨代谢之外,还具有更广泛的生理功能,其作用主要包括:参与免疫调节;参与炎性反应;糖、脂代谢的调节等病理生理过程。近年来,维生素D对免疫系统的调节作用备受关注。本文就维生素D对免疫系统的调节作用作一综述。
For a long time,the studies on function of vitamin D are concentrated on the regulation of calcium-phosphate and bone metabolism.Since vitamin D receptors were discovered in sparathyroid cells,lymphocytes,thymus,and promyelocytic cells in 1980,the knowledge of vitamin D has been broadened.Biside regulation of calcium-phosphate and bone metabolism,a wide range of physiological roles are expouded by the subsequent studies,which mainly include immune regulation,inflammatory response,and regulation of glucose and lipid metabolism.Recently,the effects of vitamin D on regulation of immunity attract dramatic attention.This paper summarizes the roles of vitamin D in regulation of immunity.
出处
《中华哮喘杂志（电子版）》
CAS
2013年第4期43-46,共4页
Chinese Journal of Asthma(Electronic Version)
基金
国家自然科学基金资助项目(81270064)
